{"title":"Towards a histological depiction in 3D imaging PET","authors":"Marios Poulos , Theodoros Felekis , Angeliki Poulou","doi":"10.1016/j.jmhi.2016.01.001","DOIUrl":null,"url":null,"abstract":"<div><p>In this study we examine the possibility of constructing metadata from Positron Emission Tomography images based on a Radial Basis Function neural network, which uses histological data extracted via the enzyme-linked immunosorbent assay abbreviation. The aim of constructing such metadata is to achieve a bringing between the binding potential receptor <em>in vitro</em> and <em>in vivo</em> Positron Emission Tomography procedures, which it is possible to calculate using a classic simplified reference tissue model. This knowledge representation procedure may then be transmitted in the Positron Emission Tomography using the testing neural network procedure. The latest satisfies the primary aim of this study, which was to avoid painful and risky biopsies of patients.</p></div>","PeriodicalId":100803,"journal":{"name":"Journal of Medical Hypotheses and Ideas","volume":"9 2","pages":"Pages S14-S23"},"PeriodicalIF":0.0000,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jmhi.2016.01.001","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Hypotheses and Ideas","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2251729416000021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In this study we examine the possibility of constructing metadata from Positron Emission Tomography images based on a Radial Basis Function neural network, which uses histological data extracted via the enzyme-linked immunosorbent assay abbreviation. The aim of constructing such metadata is to achieve a bringing between the binding potential receptor in vitro and in vivo Positron Emission Tomography procedures, which it is possible to calculate using a classic simplified reference tissue model. This knowledge representation procedure may then be transmitted in the Positron Emission Tomography using the testing neural network procedure. The latest satisfies the primary aim of this study, which was to avoid painful and risky biopsies of patients.