Evaluating the efficacy of platelet rich plasma injection for the treatment of chronic plantar fasciitis

Q3 Biochemistry, Genetics and Molecular Biology Journal of Natural Science, Biology, and Medicine Pub Date : 2020-07-01 DOI:10.4103/jnsbm.JNSBM_199_19
V. Sengodan, N. Thiagarajan, I. Raajendiren
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引用次数: 2

Abstract

Background: Plantar fasciitis is a common and recurring cause of heel pain in adults. Platelet-rich plasma (PRP) derived from autologous blood contains a high concentration of growth factors necessary for tissue healing and offer potential treatment for plantar fasciitis. Materials and Methods: The study was conducted in Coimbatore medical college hospital as a day care procedure. Between May and September 2017, 100 patients with chronic plantar fasciitis with a mean age of 40 years were included in this prospective study and were treated with single autologous PRP injection. All patients were assessed for the pain on the visual analog scale (VAS) and the American orthopedic foot and ankle score (AOFAS) both preinjection and postsingle injection of PRP. Results: The average pain perception before injection as assessed using VAS was observed to be 9.1. Before PRP injection, 72% of patients had severe limitation of activities and 28% of patients had moderate limitation of activities. Following the administration of PRP, VAS decreased to 1.6. Eighty-eight patients were completely satisfied; eight patients were satisfied with reservation, whereas four patients were unsatisfied with the treatment outcome. AOFAS improved from 52 to 90, thus establishing its therapeutic efficacy both at 8 weeks and 3 months posttreatment. Conclusion: The results of this study support that injection of autologous PRP is safe, does not affect the biomechanical function of the foot and is efficacious in improving plantar fasciitis.
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富血小板血浆注射液治疗慢性足底筋膜炎的疗效评价
背景:足底筋膜炎是成年人脚跟疼痛的常见和反复发生的原因。来自自体血液的富血小板血浆(PRP)含有高浓度的组织愈合所必需的生长因子,为足底筋膜炎提供了潜在的治疗方法。材料与方法:本研究在哥印拜陀医学院附属医院作为日间护理程序进行。2017年5月至9月期间,100名平均年龄为40岁的慢性足底筋膜炎患者被纳入这项前瞻性研究,并接受单次自体PRP注射治疗。在PRP注射前和单次注射后对所有患者进行视觉模拟评分(VAS)和美国骨科足踝评分(AOFAS)评估疼痛。结果:注射前疼痛感觉评分平均为9.1分。注射PRP前,72%的患者有严重活动受限,28%的患者有中度活动受限。给予PRP后,VAS降至1.6。88例患者完全满意;8例患者对保留满意,4例患者对治疗结果不满意。AOFAS由52分提高到90分,在治疗后8周和3个月均有明显疗效。结论:本研究结果支持自体PRP注射是安全的,不影响足部生物力学功能,对改善足底筋膜炎是有效的。
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来源期刊
Journal of Natural Science, Biology, and Medicine
Journal of Natural Science, Biology, and Medicine Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
CiteScore
2.40
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