Sequential Monte Carlo with Adaptive Weights for Approximate Bayesian Computation

Fernando V. Bonassi, M. West
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引用次数: 67

Abstract

Methods of approximate Bayesian computation (ABC) are increasingly used for analysis of complex models. A major challenge for ABC is over-coming the often inherent problem of high rejection rates in the accept/reject methods based on prior:predictive sampling. A number of recent developments aim to address this with extensions based on sequential Monte Carlo (SMC) strategies. We build on this here, introducing an ABC SMC method that uses data-based adaptive weights. This easily implemented and computationally trivial extension of ABC SMC can very substantially improve acceptance rates, as is demonstrated in a series of examples with simulated and real data sets, including a currently topical example from dynamic modelling in systems biology applications.
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具有自适应权值的序列蒙特卡罗近似贝叶斯计算
近似贝叶斯计算方法(ABC)越来越多地用于复杂模型的分析。ABC面临的一个主要挑战是克服基于先验预测抽样的接受/拒绝方法中经常存在的高拒绝率问题。最近的一些开发旨在通过基于顺序蒙特卡罗(SMC)策略的扩展来解决这个问题。在此基础上,我们引入了ABC SMC方法,该方法使用基于数据的自适应权重。ABC SMC的这种易于实现和计算琐碎的扩展可以极大地提高接受率,正如一系列模拟和真实数据集的示例所证明的那样,包括系统生物学应用中动态建模的当前热门示例。
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