Bioanalytical Method Developments for Bioanalysis of Drugs

K. Pravalika, M. Swamy, J. S. Reddy, K. A. Saraswathy, Samyuktha Metta
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Abstract

From this article, bio-analytical styles are extensively used to find the amount of medicines and their intermediate derivatives in tube matrices and the styles should be practical to acquisition in areas of mortal clinical and in human study. Bio-analytical system employed for the quantitative estimation of medicines and their metabolites in natural media and plays an essential portion in computation and rendition of BE, PK, and TK survey. The leading BA part is system improvement, system confirmation, and statistical distribution investigation. Ways similar as HPLC and LC conjugated LCMS- MS are utilized for the BA of medicines in body.
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药物生物分析的生物分析方法发展
从这篇文章中可以看出,生物分析方法被广泛应用于药物及其中间衍生物在试管基质中的含量的测定,这种方法应该在致命临床和人体研究领域具有实用性。生物分析系统用于自然介质中药物及其代谢物的定量估计,在BE、PK和TK调查的计算和再现中起着重要作用。BA的主要部分是系统改进、系统确认和统计分布调查。采用类似HPLC和LC共轭LCMS- MS的方法测定药物在体内的BA。
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