Review on Orodispersible Tablet: Recent Trends of Manufacturing of Orodispersible Tablet

Abstract

The article mainly focuses on several aspects of orodispersible tablets (ODTs). These types of tablets are those when placed in the mouth cavity disperse the drug in very rapid manner i.e. instantaneously releasing the drug which dissolve in saliva. ODTs are alternative dosage forms for the patients who are suffering from dysphasia i.e. difficulty in swallowing. The oral administration of the drug is most important method for administrating the drugs for systemic effects. Except that the parenteral route is not used routinely for self-administration e.g. insulin. The topical route is only applicable to deliver the drugs into the body for the systemic effect. The administration of the drug by the parenteral route is only beneficial for treating medical emergencies in which the subject is comatose or can’t swallow. Never the less it is probable that at least 90% of all drugs used to provide systemic effects are administered by the oral route. ODTs are different from traditional tablets in that they are designed to be dispersed on the tongue rather than swallowed whole. ODTs dissolve or disintegrate in the oral cavity without the need of water or chewing. And also it is mainly used for rapid action, to enhance the bioavailability, accurate dosing, enhance palatability, ease of administration, accurate dosing, having good patient compliance because most of the people are familiar with this route. Drugs present in ODTs do not suffer from the first-pass metabolism. This type of drug administration or delivery is becoming popular day by day due to its numerous advantages.