Prediction of Microalgae Growth Kinetics In Semi-Continuous Culture From Batch Culture Experiments

Benzidane Dehiba, Garrido-Pérez Carmen, Perales Antonio, A. El-Amine
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Abstract

due to their extensive application potential in the renewable energy, biopharmaceutical, and nutraceutical industries. For microalgal production, the choice of the photobioreactor, the method of cultivation used, and the harvesting regime adopted (batch, semi-continuous or continuous cultures) are very important. In this work, we examined the growth rate and productivity of a small volume experimental culture in batch and semi-continuous mode. Several microalgae species have been investigated for their potential as value-added products, thus we have chosen two species: green microalga ( Nannochloropsis gaditana ) and a cyanobacterium ( Arthrospira platensis ). This study develops a simple model by which biomass values in semi-continuous operation can be predicted from kinetic growth parameters obtained from a shorter batch experiment. Based on results, biomass concentrations and volumetric productivity in semi-continuous operation were successfully predicted.
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半连续培养中微藻生长动力学的批培养预测
由于其在可再生能源、生物制药和营养保健行业具有广泛的应用潜力。对于微藻的生产,光生物反应器的选择、使用的培养方法和采收制度(分批、半连续或连续培养)是非常重要的。在这项工作中,我们在批量和半连续模式下检测了小体积实验培养的生长速度和生产力。几种微藻已经被研究作为增值产品的潜力,因此我们选择了两种:绿色微藻(Nannochloropsis gaditana)和蓝藻(Arthrospira platensis)。本研究建立了一个简单的模型,通过该模型可以根据从较短的批量实验中获得的动力学生长参数预测半连续操作中的生物量值。在此基础上,成功地预测了半连续操作下的生物量浓度和体积生产力。
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