Pub Date : 2023-11-15DOI: 10.21608/eajbsc.2023.325580
Saba Beigh
----------------------
{"title":"Building Resilient Immunity Against Powassan Virus: The Necessity of A Comprehensive Immunoinformatic Approach and Coordinated T and B Cell Responses","authors":"Saba Beigh","doi":"10.21608/eajbsc.2023.325580","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.325580","url":null,"abstract":"----------------------","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"4 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136227944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-14DOI: 10.21608/eajbsc.2023.325502
Alyae Gabal, Hadeer Maria
Objective: COVID-19 survivors are either vaccinated or not usually afraid of COVID-19 side effects. This study aims to investigate post Covid-19 biochemical changes among healthy and chronically diseased either vaccinated or not subjects. Material and Method: 144 patients (72 males and 72 females) previously (two years ago) diagnosed with SARS-CoV-2 contagion by RT-PCR were enrolled as cohort group of this research. Major biochemical alterations of post Covid-19 infection among healthy, diabetic and heart-diseased Egyptian males and females either vaccinated or not were examined. Result and discussion: Results revealed that COVID-19 infection caused antioxidant levels to decrease significantly (p≤0.05) in association with a significant increase in oxidative lipid peroxidation initiating inflammation leading to deterioration of organ function (liver, heart and kidney) associated with biochemical alterations in glucose and lipid metabolism with improper immunoglobulin level. Conclusion: Chronic diseased patients were more affected by post-COVID-19 biochemical alterations. Vaccination attenuated post-COVID-19 biochemical changes. The study is expected to motivate previously infected people to check their health status and not vaccinated people to take the appropriate vaccine.
{"title":"Evaluation of Post Covid- 19 Biochemical Alterations in Normal and Chronic Diseased Egyptians: Possible Mechanisms and Role of Vaccines","authors":"Alyae Gabal, Hadeer Maria","doi":"10.21608/eajbsc.2023.325502","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.325502","url":null,"abstract":"Objective: COVID-19 survivors are either vaccinated or not usually afraid of COVID-19 side effects. This study aims to investigate post Covid-19 biochemical changes among healthy and chronically diseased either vaccinated or not subjects. Material and Method: 144 patients (72 males and 72 females) previously (two years ago) diagnosed with SARS-CoV-2 contagion by RT-PCR were enrolled as cohort group of this research. Major biochemical alterations of post Covid-19 infection among healthy, diabetic and heart-diseased Egyptian males and females either vaccinated or not were examined. Result and discussion: Results revealed that COVID-19 infection caused antioxidant levels to decrease significantly (p≤0.05) in association with a significant increase in oxidative lipid peroxidation initiating inflammation leading to deterioration of organ function (liver, heart and kidney) associated with biochemical alterations in glucose and lipid metabolism with improper immunoglobulin level. Conclusion: Chronic diseased patients were more affected by post-COVID-19 biochemical alterations. Vaccination attenuated post-COVID-19 biochemical changes. The study is expected to motivate previously infected people to check their health status and not vaccinated people to take the appropriate vaccine.","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"2 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136228892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-14DOI: 10.21608/eajbsc.2023.325503
Manar Al Fatlawi, Mahdi Al Ammar, Yasir Al Mansoori
The current study aims to detect the gene expression of genes (CCL3, miRNA-b) in Otitis Media patients and healthy persons. This finding included 50 samples collected from healthy subjects and 100 samples from a patient suffering from otitis media who attended Al-Sadr Medical City (ENT Department) in Al-Najaf Governorate during the period from February 2022 to June 2022. The samples had an average age ranging from 5 to 70 years. In this case-control study, the gene expression of these genes was compared in people with Otitis media and healthy people. PCR technique is used. The patient and control groups' samples were amplified using polymerase chain reactions. The results of the molecular study (gene expression) showed a high significant increase in the level of gene expression in patients for the two genes CCL3, miRNA146-b (9.807 ± 1.14 (6.405 ± 0.7576), respectively, compared to the control group, with a high significant difference at P≤0.05.
{"title":"Correlation Between Cytokine Gene CCL3, miRNA146-B and Otitis Media Patients in AL-Najaf Governorate, Iraq","authors":"Manar Al Fatlawi, Mahdi Al Ammar, Yasir Al Mansoori","doi":"10.21608/eajbsc.2023.325503","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.325503","url":null,"abstract":"The current study aims to detect the gene expression of genes (CCL3, miRNA-b) in Otitis Media patients and healthy persons. This finding included 50 samples collected from healthy subjects and 100 samples from a patient suffering from otitis media who attended Al-Sadr Medical City (ENT Department) in Al-Najaf Governorate during the period from February 2022 to June 2022. The samples had an average age ranging from 5 to 70 years. In this case-control study, the gene expression of these genes was compared in people with Otitis media and healthy people. PCR technique is used. The patient and control groups' samples were amplified using polymerase chain reactions. The results of the molecular study (gene expression) showed a high significant increase in the level of gene expression in patients for the two genes CCL3, miRNA146-b (9.807 ± 1.14 (6.405 ± 0.7576), respectively, compared to the control group, with a high significant difference at P≤0.05.","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"2 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136228893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.21608/eajbsc.2023.325319
Sarah AL-Huchaimi, Mahdi AL-Ammar, Sabah AL-Fatlawi
ABSTRACT
{"title":"Evaluation of Some Auto-Antibody Levels in Patients with Autoimmune Thyroiditis","authors":"Sarah AL-Huchaimi, Mahdi AL-Ammar, Sabah AL-Fatlawi","doi":"10.21608/eajbsc.2023.325319","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.325319","url":null,"abstract":"ABSTRACT","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"52 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134993238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-13DOI: 10.21608/eajbsc.2023.325177
Fatima Kadhim, Rasha Noori
----------------------
{"title":"Quantitative Assessment of Serum Specific IgE in the Diagnosis of Echinococcus granulosus","authors":"Fatima Kadhim, Rasha Noori","doi":"10.21608/eajbsc.2023.325177","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.325177","url":null,"abstract":"----------------------","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"52 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134993239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-09DOI: 10.21608/eajbsc.2023.324566
Fatima Kadhim, Rasha Noori
Five ml blood samples were obtained from fifty recurrent Echinococcosis patients. A total of 50 serum samples were collected from patients with Echinococcus granulosus and 38 serum samples from healthy humans were taken from the Al-Furat AL-Awsat Hospital, Maternity and Children Teaching Hospital and Al-Diwaniyah Teaching Hospital in Al-Diwaniyah and from Specialized Hospital for Gastroenterology and Hepatology in AL-Najaf for the period from November 2022 to April 2023. The test was performed on 5 ml of venous blood, which was collected from each sample for ELISA test to detect the positivity of oxidative stress Glutathione peroxidase (GPX). The clinical assessment of the 50 patients (who confirmed to have Echinococcosis after giving positive results by ELISA) was revealed that the frequency of distribution of patients according to sex was (74%) females and (26%) males. The differences between females and males were statistically significant (P < 0.05, P-value= 0.001). The estimated incidence of Echinococcosis increased in the 21-40 years age group, with a significant difference (P < 0.05) in comparison with the other groups. The Distribution of Hydatid Cysts according to the site of the infection was the high rate of infection in the liver compared to other organs. The concentration level of GPX decreases in patients compared with the control with a significant difference at (P ≤ 0.05). The concentration level of GPX decreased after the surgery compared with the before surgery and after surgery with a significant difference at (P ≤ 0.05).
{"title":"Role of Oxidative Stress Glutathione Peroxidase in the Detection of Patients with Echinococcus Granulosus","authors":"Fatima Kadhim, Rasha Noori","doi":"10.21608/eajbsc.2023.324566","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.324566","url":null,"abstract":"Five ml blood samples were obtained from fifty recurrent Echinococcosis patients. A total of 50 serum samples were collected from patients with Echinococcus granulosus and 38 serum samples from healthy humans were taken from the Al-Furat AL-Awsat Hospital, Maternity and Children Teaching Hospital and Al-Diwaniyah Teaching Hospital in Al-Diwaniyah and from Specialized Hospital for Gastroenterology and Hepatology in AL-Najaf for the period from November 2022 to April 2023. The test was performed on 5 ml of venous blood, which was collected from each sample for ELISA test to detect the positivity of oxidative stress Glutathione peroxidase (GPX). The clinical assessment of the 50 patients (who confirmed to have Echinococcosis after giving positive results by ELISA) was revealed that the frequency of distribution of patients according to sex was (74%) females and (26%) males. The differences between females and males were statistically significant (P < 0.05, P-value= 0.001). The estimated incidence of Echinococcosis increased in the 21-40 years age group, with a significant difference (P < 0.05) in comparison with the other groups. The Distribution of Hydatid Cysts according to the site of the infection was the high rate of infection in the liver compared to other organs. The concentration level of GPX decreases in patients compared with the control with a significant difference at (P ≤ 0.05). The concentration level of GPX decreased after the surgery compared with the before surgery and after surgery with a significant difference at (P ≤ 0.05).","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":" 20","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135292084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-08DOI: 10.21608/eajbsc.2023.324521
Safaa Almansrawi, Mohauman Alrufaie
----------------------
{"title":"Spectrophotometric Determination of Sulfanilamide Using Oxidative Coupling Reaction With the Presence of The Peroxidase Enzyme","authors":"Safaa Almansrawi, Mohauman Alrufaie","doi":"10.21608/eajbsc.2023.324521","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.324521","url":null,"abstract":"----------------------","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"56 s69","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135431453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-04DOI: 10.21608/eajbsc.2023.323606
Luma Ali, Saleem Al-Hadraawy
{"title":"Study the Role of Some Immune Markers in Patients Infected with Cutaneous Leishmaniasis","authors":"Luma Ali, Saleem Al-Hadraawy","doi":"10.21608/eajbsc.2023.323606","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.323606","url":null,"abstract":"","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"12 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135728110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-29DOI: 10.21608/eajbsc.2023.322926
Mohamed Hosney, Radwa Sallam, Mariam Sayed
----------------------
{"title":"Human Genetic as Risk Factors for COVID-19 Progression","authors":"Mohamed Hosney, Radwa Sallam, Mariam Sayed","doi":"10.21608/eajbsc.2023.322926","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.322926","url":null,"abstract":"----------------------","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"27 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136134852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-26DOI: 10.21608/eajbsc.2023.322911
Ghada El Nady, Mona Ibrahim, Gamar Gamar, Noha El-Dougdoug
----------------------
{"title":"Assessment of The Antiviral and Antiproliferation Effects of Kombucha Tea","authors":"Ghada El Nady, Mona Ibrahim, Gamar Gamar, Noha El-Dougdoug","doi":"10.21608/eajbsc.2023.322911","DOIUrl":"https://doi.org/10.21608/eajbsc.2023.322911","url":null,"abstract":"----------------------","PeriodicalId":52600,"journal":{"name":"Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology","volume":"15 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134906371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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