The Effect of Adding Epigallocatechin-3-gallate on the Porosity of Calcium Hydroxide

Kun Ismiyatin, Widya Saraswati, Caeleb Fabrizio Sudarsono
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Abstract

Background: Dental caries is a very common non-communicablae disease found in all age groups and found in 3.5 billion people in the world. Caries that harm the pulp tissue can be treated by direct or indirect pulp capping. One of the physical properties possessed by pulp capping is the porosity of material. The material most often used for pulp capping treatment of pulp perforations is calcium hydroxide (Ca(OH) 2 ). However, Ca(OH) 2 has a high pH that caused the porosity to be low. High porosity can facilitate cell development and ion exchange. Thus, additional materials with a lower pH are needed to increase porosity such as Epigallocatechin-3-gallate (EGCG). However, the porosity of the combination of EGCG with Ca(OH) 2 is still unclear, so it needs to be researched. Purpose: To explain the differences of Ca(OH) 2 porosity after the addition of EGCG. Methods: This study used a laboratory experimental study with a post test only control group design. This research using 16 samples for each control (Ca(OH) 2 – aquadest) and treatment (Ca(OH) 2 –EGCG) group. Samples from each group were subjected to freeze drying, observed with SEM, analyzed with ImageJ software, and tested with independent T-test. Results: There was a significant difference (p<0.05) in the percentage of porosity between the addition of EGCG to Ca(OH) 2 namely 32,61% compared to Ca(OH) 2 with aquadest namely 23,38%. Conclusion: The porosity of the combination of calcium hydroxide with EGCG has a higher percentage compared to calcium hydroxide with aquadest.
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表没食子儿茶素-3-没食子酸酯对氢氧化钙孔隙率的影响
背景:龋齿是一种非常常见的非传染性疾病,存在于所有年龄组,全世界有35亿人患有龋齿。损害牙髓组织的蛀牙可直接或间接盖髓治疗。盖浆所具有的物理性质之一是材料的孔隙率。髓盖治疗牙髓穿孔最常用的材料是氢氧化钙(Ca(OH) 2)。但由于Ca(OH) 2的pH值较高,导致孔隙率较低。高孔隙率有利于细胞发育和离子交换。因此,需要其他具有较低pH值的材料来增加孔隙度,例如表没食子儿茶素-3-没食子酸酯(EGCG)。但EGCG与Ca(OH) 2结合的孔隙率尚不清楚,需要进一步研究。目的:探讨EGCG对Ca(OH) 2孔隙率的影响。方法:本研究采用实验室实验研究,后验组设计。本研究采用16个样品作为对照组(Ca(OH) 2 - aquadest)和处理组(Ca(OH) 2 - egcg)。各组样品冷冻干燥,扫描电镜观察,ImageJ软件分析,独立t检验。结果:在Ca(OH) 2中添加EGCG的孔隙率为32.61%,与在Ca(OH) 2中添加aquadest的孔隙率为23.38%,差异有统计学意义(p<0.05)。结论:氢氧化钙与EGCG结合的孔隙率比氢氧化钙与aquadest结合的孔隙率高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Conservative Dentistry
Journal of Conservative Dentistry Dentistry-Dentistry (all)
CiteScore
2.10
自引率
0.00%
发文量
114
期刊介绍: The Journal of Conservative Dentistry (ISSN - 0972-0707) is the official journal of the Indian Association of Conservative Dentistry and Endodontics (IACDE). Our journal publishes scientific articles, case reports, short communications, invited reviews and comparative studies evaluating materials and methods in the fields of Conservative Dentistry, Dental Materials and Endodontics. J Conserv Dent has a diverse readership that includes full-time clinicians, full-time academicians, residents, students and scientists. Effective communication with this diverse readership requires careful attention to writing style.
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