Evaluation of Uric Acid Level and Glycemic Status in Type 2 Diabetic Patients in Rasht

Abstract

Background: Diabetes is one of the most common and costly chronic diseases with an increasing prevalence in all around the world. On the other hand, the relationship between Uric Acid (UA) level and glycemic index in type 2 diabetic patients is not clear. Objective: The aim of this study is to evaluate the UA level and glycemic status of type 2 diabetic patients. Methods: A total of 230 patients with type 2 diabetes were studied in this cross-sectional study, who referred to Razi and Besat clinics in 2020. Researcher-made checklist were used to collect demographic and clinical data includes age, sex, duration of the disease, body mass index (BMI), fasting blood sugar (FBS), Cholesterol, Triglyceride (TG), high density lipid (HDL), low density lipid (LDL), Hemoglobin A1C (HbA1c), UA, Creatinine (Cr) level, history of heart disease, blood pressure, and a history of smoking. The results were analyzed using IBM SPSS Statistics version 26. Results: The results showed that there was a marginally significant relationship between UA and HbA1C (r = 0.318, P<0.001), Cr (r = 0.351, P<0.001) and Triglyceride (TG) (r = 0.174, P=0.008). Conclusion: Generally, in patients with type 2 diabetes, serum UA level has an adverse effect on glycemic status.