Characteristic Lesions of Chest X-ray as Predictor for Multi Drug-Resistant Tuberculosis

A. Majdawati, I. Habib
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Abstract

This research aimed to demonstrate some predictors of screening diagnosis of multi drug-resistant tuberculosis (MDR-TB). Researchers determined several predictors as a screening diagnosis of MDR-TB, based on clinical symptoms, WHO criteria, chest radiographic lesions, and sputum smear microscopy. The method demonstrated a correlation between several factors as predictors of the MDR-TB diagnosis consisting of clinical symptoms, WHO criteria, BTA sputum, cross sectional chest radiograph lesions, based on examination of Gene X-pert for suspected MDR-TB. The results demonstrated a significant and a positive odds ratio value of the relationship between variables: 1). Clinical symptoms (p:0.000) with the largest percentage of coughing with shortness of breath exhibiting 51.32% and coughing exhibiting 27.9%; 2). WHO criteria are among others, new patients (p:0.000; OR:3); 3). Chest radiographic lesion: consolidation (p: 0.000; OR: 3); pleural thickening (p:0.003; OR:2); Fibrosis (p:0.000; OR:6) with location on the medial right (p:0.000; OR:2) and left inferior (p:0.000; OR:3). The BTA sputum is (p:0.000; OR:8). The predictors for screening the diagnosis of MDR-TB are coughing, and shortness of breath. Other WHO criteria include radiographic lesions, fibrosis, consolidation, pleural thickening with the location of lesions either left inferior or medial right, and positive smear sputum results. 
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胸部x线特征性病变作为多重耐药结核病的预测因子
本研究旨在探讨耐多药结核病(MDR-TB)筛查诊断的一些预测因素。研究人员根据临床症状、世卫组织标准、胸片病变和痰涂片镜检确定了几种预测因素作为耐多药结核病的筛查诊断。该方法显示了作为耐多药结核病诊断预测因素的几个因素之间的相关性,这些因素包括临床症状、世卫组织标准、BTA痰、基于疑似耐多药结核病基因X-pert检查的横断胸片病变。结果显示变量间的比值比为显著正相关:1)临床症状(p:0.000),咳嗽伴呼吸短促的比例最大,分别为51.32%和27.9%;2)世卫组织的标准包括:新患者(p:0.000;或:3);3)胸片病变:实变(p: 0.000;或:3);胸膜增厚(p:0.003;或:2);纤维化(p: 0.000;OR:6),位置在右侧内侧(p:0.000;OR:2)和左下位(p:0.000;或者:3)。BTA痰(p:0.000;或者:8)。筛查耐多药结核病诊断的预测指标是咳嗽和呼吸短促。世卫组织的其他标准包括影像学病变、纤维化、实变、胸膜增厚(病变位置为左下或右中间)以及痰涂片阳性结果。
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来源期刊
CiteScore
0.20
自引率
0.00%
发文量
20
审稿时长
4 weeks
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