Clinical and radiographic evaluations of periodontal intrabony defects treated with enamel matrix derivative: a report of two cases

Zaid R Atarchi, Mohamed T Omran, D. Miley
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Abstract

Background: Numerous studies evaluating the clinical and histologic effects of enamel matrix derivative (EMD) as an adjunct to periodontal surgical therapy have demonstrated significant improvements in clinical parameters, radiographic bone fill and periodontal regeneration. Case presentation: Two case reports are described that involved treatment of intrabony defects with periodontal flap surgery and placement of enamel matrix derivative. Each case was followed up after 12 months for clinical and radiographic evaluation. Both cases resulted in a reduction in probing depth (PD), a gain in clinical attachment level (CAL), an absence of bleeding on probing (BOP), unremarkable changes in gingival recession (REC) and radiographic evidence of bone fill. Conclusion: Treatment of an intrabony defect with periodontal flap surgery and EMD demonstrated bone fill as evidenced by radiographic evaluation performed after 12 months. Consistent improvements in the clinical parameters of CAL, PD and BOP were also noted.
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牙釉质基质衍生物治疗牙周骨内缺损的临床及影像学评价:附2例报告
背景:大量研究评估了牙釉质基质衍生物(EMD)作为牙周外科治疗辅助治疗的临床和组织学效果,表明其在临床参数、x线骨填充和牙周再生方面有显著改善。病例介绍:本文报道两例采用牙周瓣手术和牙釉质基质衍生物植入治疗骨内缺损的病例。随访12个月进行临床和影像学评价。这两个病例都导致了探探深度(PD)的减少,临床附着水平(CAL)的增加,探探时没有出血(BOP),牙龈退缩(REC)的不显著变化和骨填充的影像学证据。结论:牙周瓣手术和EMD治疗骨内缺损12个月后的影像学评价证实了骨填充。CAL, PD和BOP的临床参数也得到了一致的改善。
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