Transport of Carbon Dioxide through a Biomimetic Membrane

Efstathios Matsaridis, V. Savov, Alexandre Gritzkov, N. Zheleva, S. Gutzov
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Abstract

Biomimetic membranes (BMM) based on polymer filters impregnated with lipids or their analogues are widely applied in numerous areas of physics, biology, and medicine. In this paper we report the design and testing of an electrochemical system, which allows the investigation of CO2 transport through natural membranes such as alveoli barrier membrane system and also can be applied for solid-state measurements. The experimental setup comprises a specially designed two-compartment cell with BMM connected with an electrochemical workstation placed in a Faraday cage, two PH meters, and a nondispersive infrared gas analyzer. We prove, experimentally, that the CO2 transport through the natural membranes under different conditions depends on pH and displays a similar behavior as natural membranes. The influence of different drugs on the CO2 transport process through such membranes is discussed.
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二氧化碳通过仿生膜的运输
仿生膜(Biomimetic membrane, BMM)是基于浸渍了脂质或其类似物的聚合物过滤器,被广泛应用于物理、生物和医学的许多领域。在本文中,我们报告了一种电化学系统的设计和测试,该系统可以研究二氧化碳通过自然膜(如肺泡屏障膜系统)的运输,也可以应用于固态测量。实验装置包括一个专门设计的双室电池,BMM与放置在法拉第笼中的电化学工作站连接,两个PH计和一个非色散红外气体分析仪。我们通过实验证明,在不同条件下,CO2通过天然膜的运输取决于pH值,并表现出与天然膜相似的行为。讨论了不同药物对CO2通过这种膜运输过程的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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