{"title":"Precision Medicine for the Population—The Hope and Hype of Public Health Genomics","authors":"Junbo Wu, Nathaniel Comfort","doi":"10.48550/arXiv.2211.13183","DOIUrl":null,"url":null,"abstract":"Public health is the most recent of the biomedical sciences to embrace “precision.” Advocates for “precision public health” (PPH) call for a data-driven, computa¬tional approach to public health, leveraging genomic and other data to inform public health decision-making. Yet, like precision medicine, PPH risks overselling the value of genomic data to deter¬mine health outcomes, but on a population level. History has shown that over-emphasizing heredity tends to disproportion¬ately harm underserved minorities and disadvantaged communities. Comparing and contrasting cur¬rent PPH with an earlier attempt at using genetics to inform pub¬lic health during the Progressive era (1890–1920) highlights some potential risks of genotype-driven preventive public health.","PeriodicalId":88226,"journal":{"name":"Chance (New York, N.Y.)","volume":"6 1","pages":"25 - 27"},"PeriodicalIF":0.0000,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chance (New York, N.Y.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.48550/arXiv.2211.13183","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Public health is the most recent of the biomedical sciences to embrace “precision.” Advocates for “precision public health” (PPH) call for a data-driven, computa¬tional approach to public health, leveraging genomic and other data to inform public health decision-making. Yet, like precision medicine, PPH risks overselling the value of genomic data to deter¬mine health outcomes, but on a population level. History has shown that over-emphasizing heredity tends to disproportion¬ately harm underserved minorities and disadvantaged communities. Comparing and contrasting cur¬rent PPH with an earlier attempt at using genetics to inform pub¬lic health during the Progressive era (1890–1920) highlights some potential risks of genotype-driven preventive public health.
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