Analgesic, Anti-Inflammatory, and Antiplatelet Profile of Hydrazones Containing Synthetic Molecules

M. Asif, A. Husain
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引用次数: 39

Abstract

Hydrazones are present in many of the bioactive compounds with wide interest because of their diverse pharmacological applications. Hydrazones possess wide variety of biological activities such as anticonvulsant, antidepressant, analgesic, anti-inflammatory, antiplatelet, antimicrobial, anticancer, antihypertensive, anthelmintic, antidiabetic, antiparasitic, and other anticipated activities. This created an interest for researchers towards synthesized variety of hydrazone derivatives for different biological activities. Therefore many researchers have synthesized hydrazone derivatives as target structures for their biological activities. This is paper focuses on the analgesic, anti-inflammatory, and antiplatelet activities of hydrazones.
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含合成分子的腙类化合物的镇痛、抗炎和抗血小板谱
腙类化合物存在于许多生物活性化合物中,具有广泛的药理作用。腙类化合物具有广泛的生物活性,如抗惊厥、抗抑郁、镇痛、抗炎、抗血小板、抗菌、抗癌、降压、驱虫药、降糖、抗寄生虫等预期活性。这引起了研究人员对合成各种具有不同生物活性的腙衍生物的兴趣。因此,许多研究者合成了腙衍生物作为其生物活性的靶结构。本文主要研究腙类化合物的镇痛、抗炎和抗血小板活性。
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