Combretum hypopilinum exhibited anti-inflammatory activity in LPS-stimulated RAW 264.7 murine macrophages through inhibition of inflammatory mediators and apoptosis
K. Idoh, K. Dosseh, Mrinmoy Gautam, Tchazou Kpatcha, N. Manikandan, A. Agbonon, M. Ramanathan, M. Gbéassor
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Abstract
This study has investigated the effects of Combretum hypopilinum on lipopolysaccharide (LPS)-induced inflammation in RAW 264.7 cells. Dried root bark of C. hypopilinum was extracted with dichloromethane, ethyl acetate, and ethanol to give three extracts. To select the most protective extract, RAW 264.7 cells were treated with each extract (10, 20, 40
期刊介绍：
Journal of Applied Pharmaceutical Science (JAPS) is a monthly, international, open access, journal dedicated to various disciplines of pharmaceutical and allied sciences. JAPS publishes manuscripts (Original research and review articles Mini-reviews, Short communication) on original work, either experimental or theoretical in the following areas; Pharmaceutics & Biopharmaceutics Novel & Targeted Drug Delivery Nanotechnology & Nanomedicine Pharmaceutical Chemistry Pharmacognosy & Ethnobotany Phytochemistry Pharmacology & Toxicology Pharmaceutical Biotechnology & Microbiology Pharmacy practice & Hospital Pharmacy Pharmacogenomics Pharmacovigilance Natural Product Research Drug Regulatory Affairs Case Study & Full clinical trials Biomaterials & Bioactive polymers Analytical Chemistry Physical Pharmacy.
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