Arit Okechukwu Nwogu, D. Tamuno-Emine, A. Ben-Chioma, E. Bartimaeus
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引用次数: 0
Abstract
Plants are major sources used in the production of pharmaceutically active drugs and they contain diverse phytochemicals which give these herbal supplements their biological and pharmacological effects. This study evaluated the phytochemical constituents of some commonly sold male herbal fertility supplements (Libron Herbal, Mascum Herbal Pride and Energy 3000) in Port Harcourt, Nigeria. The qualitative and quantitative analysis of the herbal supplements was done using standard procedures. The GC 789OB 5977A and Mass Spectrometry Device (MSD) Model was used for the GC/MS Study. Results of the qualitative phytochemical analysis of the supplements shows that flavonoid, protodiocin, tannins, phenols and alkaloids were present in libron herbal supplement. Protodiocin, saponins, tannins, phenols, alkaloids and cardiacglycosides were present in mascum herbal supplement while flavonoids, protodiocin, tannins, alkaloids, anthroquinones and terpeniods were present in Energy 3000 herbal supplement. For the quantitative phytochemical analysis of the herbal supplements, libron herbal supplement contained Flavonoid 0.24 ± 0.00%, protodiocin 0.29 ± 0.01%, tannins 0.37 ± 0.02%, phenols 0.18 ± 0.00% and alkaloid 0.28 ± 0.10%. Mascum herbal supplement were seen to contain protodiocin 0.27 ± 0.07%, saponins 0.48 ± 0.08%, tannis 0.38 ± 0.06%, phenols 0.21± 0.07%, alkaloids 0.18 ± 0.10%, and cardiaglycosides 0.27 ± 0.07% while Energy 3000 was made up of flavonoid 0.10 ± 0.00%, protodiocin 0.29 ± 0.04%, tannis 0.64 ± 0.10%, phenols 0.28 ± 0.01%, alkaloids 0.26 ± 0.01%, anthroquinones 0.27 ± 0.10% and terpenoids 0.25 ± 0.00%.The GC/MS study was seen to contain various chemical compunds. The three herbal supplements assayed contain diverse phytochemicals that may enhance male fertility as well as some chemical compounds that could alter hormonal functioning of some biochemical systems in the albino rats.
植物是生产药用活性药物的主要来源,它们含有多种植物化学物质,使这些草药补充剂具有生物学和药理作用。本研究评估了尼日利亚哈科特港一些常见的男性草药生育补充剂(Libron herbal, Mascum herbal Pride and Energy 3000)的植物化学成分。采用标准程序对草药补充剂进行定性和定量分析。GC - 789OB - 5977A和质谱仪(MSD)模型用于GC/MS研究。定性植物化学分析结果表明,天秤座草药补品中含有黄酮类、原薯蓣皂苷、单宁、酚类和生物碱。mascum中草药补品中含有原薯蓣皂苷、皂苷、单宁、酚类、生物碱和心苷类;Energy 3000中草药补品中含有黄酮类、原薯蓣皂苷、单宁、生物碱、蒽醌类和萜类。在植物化学定量分析中,黄酮类化合物含量为0.24±0.00%,原薯蓣皂苷含量为0.29±0.01%,单宁含量为0.37±0.02%,酚类化合物含量为0.18±0.00%,生物碱含量为0.28±0.10%。Mascum中草药补品中原薯蓣皂苷含量为0.27±0.07%,皂苷含量为0.48±0.08%,单宁含量为0.38±0.06%,酚类含量为0.21±0.07%,生物碱含量为0.18±0.10%,糖苷含量为0.27±0.07%;Energy 3000中黄酮类含量为0.10±0.00%,原薯蓣皂苷含量为0.29±0.04%,单宁含量为0.64±0.10%,酚类含量为0.28±0.01%,生物碱含量为0.26±0.01%,蒽醌类含量为0.27±0.10%,萜类含量为0.25±0.00%。GC/MS研究发现含有多种化合物。这三种草药补充剂含有不同的植物化学物质,可以提高雄性的生育能力,也含有一些化合物,可以改变白化大鼠体内某些生化系统的激素功能。
期刊介绍:
The SEAMEO* Regional Tropical Medicine and Public Health Project was established in 1967 to help improve the health and standard of living of the peoples of Southeast Asia by pooling manpower resources of the participating SEAMEO member countries in a cooperative endeavor to develop and upgrade the research and training capabilities of the existing facilities in these countries. By promoting effective regional cooperation among the participating national centers, it is hoped to minimize waste in duplication of programs and activities. In 1992 the Project was renamed the SEAMEO Regional Tropical Medicine and Public Health Network.