Antibiotic Sensitivity Of Acid Stressed Probiotic Lactobacillus Acidophilus Ncdc 291

K. NattN, S. Garcha
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引用次数: 2

Abstract

LAB (Lactic Acid Bacteria)-Lactobacillus acidophilus, a major inhabitant of gastrointestinal tract of human beings is used as a probiotic. Antibiotics taken during illness not only kill the disease causing microorganisms but also disrupt the normal microbial balance of the gut leading to a number of side effects and encouraging the patients to restore their natural gut microflora with the intake of probiotics. A well known probiotic Lactobacillus acidophilus NCDC 291 was used in the present study and its resistance towards antibiotics was determined at optimum pH and also by growing it under acid stressed conditions. Studies revealed that culture adapted to acid stressed conditions had increased resistance towards antibiotics than that grown at optimum pH.
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酸应激益生菌嗜酸乳杆菌Ncdc 291的抗生素敏感性
乳酸菌(lactobacillus lactoophilus)-嗜酸乳杆菌(lactobacillus Acid ophilus)是人类胃肠道的主要居民,被用作益生菌。在患病期间服用抗生素不仅可以杀死致病微生物,而且还会破坏肠道的正常微生物平衡,导致许多副作用,并促使患者通过摄入益生菌来恢复其天然肠道微生物群。本研究使用了一种著名的益生菌嗜酸乳杆菌NCDC 291,并在最佳pH和酸胁迫条件下测定了其对抗生素的耐药性。研究表明,适应酸胁迫条件的培养物比在最佳pH条件下生长的培养物对抗生素的耐药性增加。
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