Supervivencia de los niños con Leucemia Linfoide Aguda manejados con protocolo Basado en ALL-IC-BFM 2009 en Bogotá D.C. Colombia.

Abstract

Introduction: Acute Lymphoid Leukemia is the most frequent neoplasm in childhood, and therefore, the treatment strategy and access to each of the interventions are defining aspects in the patient's cure. Objectives: To determine the overall and event-free survival of patients with Acute Lymphoid Leukemia treated with a strategy based on the Intercontinental Berlin Frankfurt and Munster Acute Lymphoid Leukemia protocol (ALL-IC-BFM 2009) with a permanent administrative follow-up program to which they are admitted. The patient once the oncological diagnosis is made. To establish the patients' survival according to the assigned risk group and describe the relapse rate in the evaluated group. Methods: 51 patients under 18 years of age diagnosed with Acute Lymphoid Leukemia, treated with the ALL-IC-BFM 2009 strategy, entered the comprehensive care program for cancer patients at the Colsubsidio Children's Clinic, were followed for four years. Observational prospective cohort study with survival analysis. Results: Overall survival for the 4-year cohort was 71.1%, while event-free survival was 69.4%. According to the risk groups, the overall survival was 89%; for the standard risk, it was 85.2% for the intermediate-risk group and 39.8% for the high-risk group. Conclusions: Overall survival behaved as reported in the region; however, the results obtained in standard and intermediate-risk patients exceeded overall survival.