Krzysztof Szymoński , Ewelina Lipiec , Kamila Sofińska , Katarzyna Skirlińska-Nosek , Katarzyna Milian-Ciesielska , Joanna Szpor , Michał Czaja , Sara Seweryn , Natalia Wilkosz , Giovanni Birarda , Federica Piccirilli , Lisa Vaccari , Marek Szymoński
{"title":"Spectroscopic screening of pancreatic cancer","authors":"Krzysztof Szymoński , Ewelina Lipiec , Kamila Sofińska , Katarzyna Skirlińska-Nosek , Katarzyna Milian-Ciesielska , Joanna Szpor , Michał Czaja , Sara Seweryn , Natalia Wilkosz , Giovanni Birarda , Federica Piccirilli , Lisa Vaccari , Marek Szymoński","doi":"10.1016/j.clispe.2021.100016","DOIUrl":null,"url":null,"abstract":"<div><p>Pancreatic cancer is one of the most aggressive and lethal malignant neoplasms in the world and 5-year survival rate still remains below 10%. Although, there are many reasons for that, one definitely is the lack of early and unique diagnostic tools for pancreatic cancer screening, which somehow correlates with no sufficient knowledge about cancer’s molecular nature. This article aims to prove the concept that an application of molecular spectroscopic methods including FTIR hyperspectral imaging and Raman hyperspectral mapping, combined with proper tissue pre-processing and analytical algorithms, allows differentiating benign and malignant pancreatic glands with good precision.</p></div>","PeriodicalId":100277,"journal":{"name":"Clinical Spectroscopy","volume":"3 ","pages":"Article 100016"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666054721000119/pdfft?md5=b7863da342b50d5c8f5b76e6784aa075&pid=1-s2.0-S2666054721000119-main.pdf","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Spectroscopy","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666054721000119","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10
Abstract
Pancreatic cancer is one of the most aggressive and lethal malignant neoplasms in the world and 5-year survival rate still remains below 10%. Although, there are many reasons for that, one definitely is the lack of early and unique diagnostic tools for pancreatic cancer screening, which somehow correlates with no sufficient knowledge about cancer’s molecular nature. This article aims to prove the concept that an application of molecular spectroscopic methods including FTIR hyperspectral imaging and Raman hyperspectral mapping, combined with proper tissue pre-processing and analytical algorithms, allows differentiating benign and malignant pancreatic glands with good precision.
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