Risk factors for endometrial polyps’ development in reproductive-age women

Abstract

Endometrial polyps are the most commonly observed pathological finding in the uterus. However, to date, there is little data regarding the factors for the development of endometrial polyps in reproductive-age women. This fact determined the direction of our study. A search was conducted among scientific papers in the Science Direct, CochraneLibrary, PubMed databases by keywords (polyps, endometrium, risk factors, reproductive age) for 1994–2022. As a result of the analysis of the scientific literature, we came to the following conclusions: 1. The prevalence of endometrial polyps depends on the studied population, while the actual prevalence is difficult to determine, since the endometrial polyps can be asymptomatic and regress over time. 2. Implementation of endometrial polyps, apparently, depend not on one, but on many factors: genetic, hormonal, metabolic, medicinal. 3. Increasing the amount of endogenous estrogen, the introduction of exogenous estrogen without progesterone component and age are the most important predisposing risk factors for the development of endometrial polyps.