Possible strategies and treatments of SARS-CoV-2 outbreak

Abstract

December 2019 in Wuhan, Hubei, China, pneumonia-like cases with unexplored cause appeared, after sequence analysis named as SARS-COV-2. WHO reported the prevalence of tobacco addiction was 19.33%, with 23.29% male and 15.35% female adolescents in 133 countries of the world. History revealed it is a type of common virus spreading epidemic in animals: people, birds, bats mostly harbor these viruses. Bats, pigs, civets, and pangolins are to be intermediate species for the new coronavirus. Coronaviruses cause long term and constant effect due to their ability to adapt to the new environment and host by mutation; recombination as dependent RNA polymerase and error-prone RNA. Four genera of Coronaviruses are Alpha, Beta, Gamma, and Delta coronaviruses respectively. HCOV-NL63, TGEV, PEDV are alpha coronaviruses. SARS-CoV, MERS-CoV, OC43 are beta coronaviruses. IBV, PdCoV are gamma and delta coronaviruses, respectively. This outbreak would be controlled under the guideline of prevention and maintain hygienic conditions.