Alteration of consciousness via diverse photo-acoustic stimulatory patterns. Phenomenology and effect on salivary flow rate, alpha-amylase and total protein levels

Anita Beck , Gábor Fábián , Pál Fejérdy , Wolf-Rainer Krause , Péter Hermann , Károly Módos , Gábor Varga , Tibor Károly Fábián
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Abstract

Long-term photo-acoustic stimulation is used for the induction of altered states of consciousness for both therapeutic and experimental purposes. Long-term photo-acoustic stimulation also leads to changes in the composition of saliva which have a key contribution to the efficiency of this technique in easing mucosal symptoms of oral psychosomatic patients. The aim of this study is to find out whether there is any cumulative effect of repeated stimulation and whether there are any detectable differences between diverse stimulatory patterns of long lasting photo-acoustic stimulation on the phenomenology of the appearing trance state and on salivary secretion. There was significant cumulative effect in relation with the appearance of day dreaming as phenomenological parameter, and in relation with protein output and amylase/protein ratio as salivary parameter. Pattern specific effect was detectable in relation with salivary flow rate only. Although our results clearly indicate the existence of certain cumulative and stimulation-pattern specific effects of repeated photo-acoustic stimulation, the absolute values of all these effects were relatively small in this study. Therefore, in spite of their theoretical importance there are no direct clinical consequences of these findings. However, our data do not exclude at all the possibility that repeated stimulation with other stimulatory parameters may lead to more pronounced effects. Further studies are needed to make clear conclusion in this respect.

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通过不同的光声刺激模式改变意识。对唾液流速、α -淀粉酶和总蛋白水平的影响
长期光声刺激用于诱导意识状态的改变,用于治疗和实验目的。长期光声刺激也会导致唾液成分的变化,这对该技术在缓解口腔心身患者的粘膜症状方面的效率有关键贡献。本研究的目的是研究重复刺激是否存在累积效应,以及长时间光声刺激的不同刺激模式在出现恍惚状态的现象学和唾液分泌方面是否存在可检测的差异。现象参数与白日做梦的出现有关,唾液参数与蛋白质输出和淀粉酶/蛋白质比值有关,均有显著的累积效应。模式特异性效应仅与唾液流量有关。虽然我们的研究结果清楚地表明,重复光声刺激存在一定的累积效应和刺激模式特异性效应,但在本研究中,所有这些效应的绝对值都相对较小。因此,尽管这些发现在理论上具有重要意义,但它们并没有直接的临床结果。然而,我们的数据完全不排除其他刺激参数的重复刺激可能导致更明显的效果。在这方面需要进一步的研究得出明确的结论。
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来源期刊
Journal of Physiology-Paris
Journal of Physiology-Paris 医学-神经科学
CiteScore
2.02
自引率
0.00%
发文量
0
审稿时长
>12 weeks
期刊介绍: Each issue of the Journal of Physiology (Paris) is specially commissioned, and provides an overview of one important area of neuroscience, delivering review and research papers from leading researchers in that field. The content will interest both those specializing in the experimental study of the brain and those working in interdisciplinary fields linking theory and biological data, including cellular neuroscience, mathematical analysis of brain function, computational neuroscience, biophysics of brain imaging and cognitive psychology.
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