Lafuente Cevallos Lizeth Veronica, Urena Lopez Valeria Alex, Ra, Lascano Gallegos Nathalie, Palacios Alvarez Santiago Alberto
{"title":"Epidermolysis Bullosa Acquisita: A Case Report","authors":"Lafuente Cevallos Lizeth Veronica, Urena Lopez Valeria Alex, Ra, Lascano Gallegos Nathalie, Palacios Alvarez Santiago Alberto","doi":"10.35248/2155-9554.11.S7.546","DOIUrl":null,"url":null,"abstract":"Epidermolysis Bullosa Acquisita (EBA) is a chronic autoimmune subepidermal blistering disease developed after damage to type VII collagen by autoantibodies. Type VII collagen is the major component of anchoring fibrils in the sub-lamina densa hemidesmosomes of the skin and squamous mucosas. The worldwide incidence is estimated between 0.2-0.5/million inhabitants per year. Two major clinical variants have been described: the mechanobullous, and the inflammatory EBA.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"15 1","pages":"1-2"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical & experimental dermatology research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35248/2155-9554.11.S7.546","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Epidermolysis Bullosa Acquisita (EBA) is a chronic autoimmune subepidermal blistering disease developed after damage to type VII collagen by autoantibodies. Type VII collagen is the major component of anchoring fibrils in the sub-lamina densa hemidesmosomes of the skin and squamous mucosas. The worldwide incidence is estimated between 0.2-0.5/million inhabitants per year. Two major clinical variants have been described: the mechanobullous, and the inflammatory EBA.
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