Autoimmune Diseases a Late Complication of Toxic Epidermal Necrolysis: A Case Report

Abstract

Background: Toxic Epidermal Necrolysis (TEN) is a serious adverse drug reaction causing a potentially fatal mucocutaneous bullous rash and epithelial detachment. It is increasingly recognized that survivors may develop late sequelae, some of which may be associated with significant morbidity. Few studies have mentioned autoimmune diseases as late complications of TEN. Case report: We report the case of a patient hospitalized for TEN who developed long-term Hashimoto’s thyroiditis and Sjögren’s syndrome. Conclusion: Toxic epidermal necrolysis has a major impact on long-term quality of life. A prolonged multidisciplinary follow-up including a social follow-up is necessary.