Comparative efficacy of the Antiplaque Effect of Natural Honey Mouthwash and Chlorhexidine Mouthwash. A randomized controlled trial

Muhammad Abid, Saima Quareshi, Tazeen Zehra
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Abstract

Objectives: To compare the efficacy of natural Honey (10%) and chlorhexidine mouthwash (0.12%) on the dental plaque levels. Moreover, to evaluate the efficacy of natural Honey and chlorhexidine mouthwash on the level of dental plaque. Methods: This study was a single-centered randomized controlled trial conducted on participants attending the Dental OPD of Dar-ul-Sehat hospital in Karachi. A total of 60 participants were included in the trial from June 2020 to December 2020. The sample size was calculated using openepi after entering the mean and SD of the honey and chlorhexidine groups. The study included sixty male and female participants ranging in age from 18 to 25 years, and those with medical illness, missing teeth, and antimicrobial history were excluded from the study. The subjects were randomly assigned to two groups: Natural Honey or Chlorhexidine gluconate mouthwash. The data was collected at the baseline and 14th day; the plaque was revealed using a disclosing solution. Their scores were recorded at four sites per tooth using the Silness-Loe plaque index criteria. Later, statistical analysis was performed to compare the effects of the two groups. P ? 0.05 was considered statistically significant. Results: Our findings revealed that both groups effectively lowered the plaque score. However, it showed a more significant reduction in plaque indices in the honey group on Day 14 when compared to chlorhexidine mouthwash. Conclusion: Honey has been identified as a potent antibacterial agent with therapeutic properties. Based on the findings of this study, it is possible to conclude that gargling with the original honey 10% solution is effective in lowering dental plaque score. Honey can be used in relation to conventional treatments to protect dental plaque and gingivitis. More research will be needed to back up these preliminary findings. Moreover, the synergistic effect of Chlorhexidine with natural Honey must be investigated
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天然蜂蜜漱口水与氯己定漱口水抗牙菌斑效果的比较。随机对照试验
目的:比较天然蜂蜜(10%)和氯己定漱口水(0.12%)对牙菌斑水平的影响。此外,评估天然蜂蜜和氯己定漱口水对牙菌斑水平的影响。方法:本研究是一项单中心随机对照试验,研究对象是在卡拉奇Dar-ul-Sehat医院牙科门诊就诊的患者。从2020年6月至2020年12月,共纳入60名受试者。输入蜂蜜组和氯己定组的平均值和标准差后,用openepi计算样本量。该研究包括60名年龄在18到25岁之间的男性和女性参与者,那些有疾病、缺牙和抗微生物史的人被排除在研究之外。受试者被随机分为两组:天然蜂蜜组和葡萄糖酸氯己定漱口水组。在基线和第14天收集数据;用揭露液把斑块显露出来。他们的分数被记录在每颗牙齿的四个部位,使用的是silness - love菌斑指数标准。随后进行统计学分析,比较两组疗效。P ?0.05认为有统计学意义。结果:我们的研究结果显示,两组都有效地降低了斑块评分。然而,在第14天,与氯己定漱口水相比,蜂蜜组的斑块指数下降得更显著。结论:蜂蜜是一种有效的抗菌药物。根据这项研究的结果,可以得出结论,用10%的原始蜂蜜溶液漱口对降低牙菌斑评分是有效的。蜂蜜可以用于常规治疗,以保护牙菌斑和牙龈炎。需要更多的研究来支持这些初步发现。此外,还需研究氯己定与天然蜂蜜的协同作用
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