Platinum and Copper Supported in Functionalized Titania Nanoparticles for the Treatment of Cervical and Prostate Cancer

Abstract

Today, cancer is one of the main causes of mortality. The most common treatments are chemotherapy, surgery, radiology and radiosurgery. The catalytic nanomedicine is a new research branch focused on the preparation of nanobiomaterials with medical applications to create a targeted therapy. The goal of this study was to determine the cytotoxic effect of the platinum nanoparticle (NPt) and the copper nanoparticle (NP-Cu) in lines of cancer cells as well as healthy cells for the cervical uterus cancer (HeLa), prostate cancer (DU 145). The catalyst nanoparticles used to break the bonds C-C, C-N and C=O in nitrogenous bases were synthesized in a sol-gel process. It is proven that they were biocompatible and non-toxic. Cell barriers were crossed with platinum and copper supported on functionalized titania (TiO2). In vitro tests were performed giving as a result that the NPt nanoparticles are much slower than the NP-Cu ones.