Basic research of the regulation mechanisms of trichothecene production for reduction of the mycotoxin contamination

Mycotoxins Pub Date : 2014-01-01 DOI:10.2520/MYCO.64.69
Kazuyuki Maeda, Y. Nakajima, Hinayo Ichikawa, Y. Kitou, T. Kosaki, Tamio Saito, T. Motoyama, H. Osada, Tetsuo Kobayashi, M. Kimura
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Abstract

Novel bioactive substances that regulate trichothecene production are in great demand both as tools for basic research and as control agents for reduction of mycotoxin contamination. Using compounds from the RIKEN Natural Product Depository (NPDepo) library, we are now screening for activators and inhibitors of trichothecene production. In this symposium, we describe the outlines of our recent progress on the regulation mechanisms of trichothecene production.
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减少霉菌毒素污染的霉菌烯生产调控机制的基础研究
作为基础研究的工具和减少霉菌毒素污染的控制剂,对调节霉菌烯生产的新型生物活性物质的需求很大。利用RIKEN天然产物库(NPDepo)库中的化合物,我们现在正在筛选毛霉烯生产的活化剂和抑制剂。在本次研讨会上,我们概述了我们在毛藻烯生产调控机制方面的最新进展。
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