{"title":"The synaptic cleft of the neuromuscular junction","authors":"Joshua R. Sanes","doi":"10.1016/S1044-5781(06)80026-5","DOIUrl":null,"url":null,"abstract":"<div><p>The basal lamina (BL) that ensheaths each skeletal musclefiber passes between the pre- and postsynaptic membranes at the neuromuscular junction. A consequence of this arrangement is that BL comprises much of the synaptic cleft material of this synapse. Some of the cues that guide differentiation and regeneration of both pre- and postsynaptic components are stably associated with synaptic BL. This paper reviews studies aimed at identifying these components and learning how they work.</p></div>","PeriodicalId":101155,"journal":{"name":"Seminars in Developmental Biology","volume":"6 3","pages":"Pages 163-173"},"PeriodicalIF":0.0000,"publicationDate":"1995-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1044-5781(06)80026-5","citationCount":"34","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in Developmental Biology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1044578106800265","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 34
Abstract
The basal lamina (BL) that ensheaths each skeletal musclefiber passes between the pre- and postsynaptic membranes at the neuromuscular junction. A consequence of this arrangement is that BL comprises much of the synaptic cleft material of this synapse. Some of the cues that guide differentiation and regeneration of both pre- and postsynaptic components are stably associated with synaptic BL. This paper reviews studies aimed at identifying these components and learning how they work.