Controllable Fabrication and Characterization of Gold Nanoparticles: Enhanced Therapeutic Approaches in Cancer

Abstract

Energy trans-ducting gold nano-particles, with well-being physical, chemical and optical properties for utilization in different types of cancer therapy can be prepared through chemical seed growth reduction method. Gold nano particle is a umbrella term have a variety of size and shape. More regular gold nano-particles can be obtained by reduction of HAuCl4, selection of chemicals and parameters of growth medium are set in accordance with the required category of nano-particles. Nano-particles have longest dimension of 100 nm. Therapeutic treatments like photo-imaging, gene delivery, drug delivery, cell labeling and photo thermal therapy   can be done by gold nano particles.  They reduce the side effects of conventional therapy due to high target specificity and absorb and scatter specific wavelength of laser. Hyperthermia in cancerous cells is generated without damaging surrounding healthy tissues, cause the cell death by necrosis and apoptosis. The overall morphology of gold nano particles can be characterized by SEM and TEM.