PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF MEDHYA RASAYANA TABLET- A COMPOUND AYURVEDIC FORMULATION

Abstract

ABSTARCT Behavioral problem in young children is Very common. Enuresis is defined as the voluntary or involuntary repeated discharge of urine into clothes or bed. This problem greatly affects psychosocial life of child as well as family members. It affects small to middle age group of children mainly. It is considered as multifactorial behavioral disorder.1 In Ayurvedic classics, the brief description regarding Shayyamutra is found in Sharangadhara2 and Vangasena Samhita3. This disease mainly involved Vata (Apan Vayu), Pitta (Pachaka), Kapha (Tarpaka), along with Manasika Dosha Tama. There are many treatment option are now available for disease but traditionally very less information was available for the same. Medhya Rasayana is compound of Ayurvedic formulation mentioned in Charak Samhita text for the treatment of various psychiatry illnesses4. Medhya Rasayana contais Brahmi, Shankhapushpi, Yastimadhu, Guduchi. The present study was carried out to standardize the finished product Medhya rasayana to confirm its identity, purity and quality. The presence of Epidermal cells, Colonchyma cells, Starch grains, Covering trichoma, Crystal fibers, Pitted vessels, Rhomboidal crystals, Cork cell etc were the characteristic features of observed in microscopy of drug. Physico chemical analysis shows loss on drying is 4.88% w/w, water soluble extract is 13.9% w/w, methanol soluble extract is 9.48% w/w, ash value is 5.20% w/w and PH is 6.0. High Performance Thin Layer Chromatography (HPTLC) at 254 nm and 366 nm resulted into 8 & 7 spots respectively. World Journal of Pharmaceutical Research SJIF Imp ct Factor 7.523 Volume 6, Issue 11, 668-675. Research Article ISSN 2277– 7105