INFLUENCE OF INTRAPERITONEAL ADMINISTRATION OF CERIUM OXIDE ON BLOOD PARAMETERS AND LIPID PROFILE IN MICE (MUS MUSCULUS)

Abstract

Purpose: White laboratory mice Mus musculus L. strain BALB / C were used to study the effects cerium oxide on the hematological parameters and lipid profile values. Results: Results showed a significant decrease (p≤0.05) in the RBCs' hemoglobin Hb 'and PCV' parameters as well as the presence of a significant in the mean erythrocyte MCV volume in the two doses (2.5'and .3.75) micro liters / kg ' , while there was no significant difference in hemoglobin (MCH) and the mean concentration of hemoglobin in red blood cells (MCHC) when compared with the control group, while the two doses did not differ significantly in PCV, Hb, RBCs, while the two doses differed significantly between them in MCV. There is significant difference in the level of triglycerides (TG, LDL) and HDL (compared with the control group) for both doses, and it was found that there was a significant difference between the low and high dose (2.'3.75) micro liters / kg in the HDL level. TG, LDL) compared with the control group at the probability level (P≤0.05), while there was no difference between the high and low dose in the level of cholesterol and (VLDL).