THE USE OF IMPLICIT ASSOCIATIONS TEST FOR DIAGNOSING ALCOHOL DEPENDENCE

G.O. Usialionak, A. A. Kirpichenka, A. F. Martsinkevich
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Abstract

Alcohol dependence syndrome is a severe disease that affects not only the health but also the social functioning of a person and leads to dangerous consequences. Early diagnosis of this disease will help to minimize the damage. Objectives. To develop a method for diagnosing alcohol dependence syndrome by means of implicit associations test. Material and methods. The indices of passing the implicit associations test by 152 patients with the diagnosis «Alcohol dependence syndrome», who made up the control group, and those of 189 practically healthy volunteers were investigated. The statistical analysis was made in R 4.0.3 format. To build the model, multiple logistic regression was used, the quality of which was assessed using ROC analysis. The differences were considered statistically significant at p-value <0.05. Results. These values were used to build a logistic regression model. The resulting model has a high predictive power - sensitivity and specificity made up 90.32% and 67.74%, respectively, AUC (area under the curve) and Fmes (general characteristics of predictive power) were 88.06% and 83.17%, correspondingly. Conclusions. As a result of the work carried out, a highly sensitive method for diagnosing alcohol dependence syndrome using an implicit associations test has been developed, which can be used for screening and diagnosing, as well as for dynamic observation of patients with alcohol dependence syndrome.
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内隐联想测验在酒精依赖诊断中的应用
酒精依赖综合症是一种严重的疾病,不仅影响一个人的健康,而且影响一个人的社会功能,并导致危险的后果。这种疾病的早期诊断将有助于减少损害。目标。目的:建立内隐联想测验诊断酒精依赖综合征的方法。材料和方法。研究了152例诊断为“酒精依赖综合征”的患者作为对照组和189名实际健康志愿者的内隐联想测验通过指数。采用r4.0.3格式进行统计分析。采用多元logistic回归建立模型,采用ROC分析评价模型的质量。p值<0.05认为差异有统计学意义。结果。这些值被用来建立一个逻辑回归模型。该模型具有较高的预测能力,灵敏度为90.32%,特异度为67.74%,曲线下面积(AUC)为88.06%,预测能力一般特征Fmes为83.17%。结论。由于所开展的工作,已经开发出一种使用内隐关联测试诊断酒精依赖综合征的高灵敏度方法,可用于筛查和诊断,以及对酒精依赖综合征患者的动态观察。
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