Tetanus Presented as Hemiparesis and Facial Dystonia

J. Dulski, M. Schinwelski, M. Dubaniewicz, J. Sławek
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Abstract

We report a case of tetanus presenting as the facial dystonia and hemiparesis with complete recovery and video accompanied follow-up. A 78-year-old male, who sustained an abrasion to his right forearm, presented with dysarthria, dysphagia, prominent involuntary painful muscle spasms in the face, blepharospasm, risus sardonicus, trismus (lockjaw), neck muscle rigidity and mild weakness of the distal right upper extremity. The combined treatment of human antitetanus immunoglobulin, tetanus vaccine, penicillin, metronidazole and diazepam were given with no effect. He continued to worsen and due to the risk of the respiratory failure (finally not developed) he was sent to the Intensive Care Unit. The combined treatment was continued, and his symptoms started to improve within 2 weeks. As the muscle rigidity has been improving, the patient developed significant right hemiparesis. The imaging of the brain and cervical spine found no significant pathology. At the follow-up visits the patient presented only slightly impaired dexterity of the right hand that gradually resolved. There are many reports of unusual presentations of tetanus, however, hemiparesis is uncommon, and to our knowledge, only one case was reported in the literature. We highlight the variability of clinical presentation of tetanus, the need to consider tetanus in cases of rapidly evolving muscle spasms following peripheral injuries and provide the guidelines on tetanus prophylaxis.
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破伤风表现为偏瘫和面部肌张力障碍
我们报告一例破伤风的表现为面部肌张力障碍和偏瘫完全恢复和视频伴随随访。78岁男性,右前臂磨损,表现为构音障碍、吞咽困难、面部明显的不自主疼痛性肌肉痉挛、眼睑痉挛、结节状虹膜、牙关紧闭(锁颌)、颈部肌肉僵硬和右上肢远端轻度无力。人抗破伤风免疫球蛋白、破伤风疫苗、青霉素、甲硝唑、地西泮联合治疗均无效果。他继续恶化,由于呼吸衰竭的风险(最后没有发展),他被送往重症监护室。持续联合治疗,2周后症状开始好转。随着肌肉刚性的改善,患者出现了明显的右半瘫。脑及颈椎影像学检查未见明显病变。在随访中,患者仅表现出轻微的右手灵巧性受损,并逐渐消退。有许多报告破伤风的不寻常的表现,然而,偏瘫是不常见的,据我们所知,只有一个病例在文献中被报道。我们强调破伤风临床表现的可变性,需要考虑破伤风在周围损伤后迅速发展的肌肉痉挛的情况下,并提供破伤风预防指南。
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