Renal Synovial Sarcoma- A Rare Primary Malignancy

Khurana Cs
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Abstract

Synovial sarcoma (SS) is a tumour of the soft tissues with a unique chromosomal translocation t(X;18)(p11.2;q11.2) detected by polymerase chain reaction in tissue homogenates. A 36 years old woman, with complaints of pain and lump in left flank was found to have a large lump occupying the left flank, left hypochondrium and the umbilical region, which was bimanually palpable and did not cross the midline. Investigations were suggestive of left RCC for which patient was operated. Intraoperatively, a tumour mass was seen replacing the whole kidney with involvement of left adrenal gland. Histopathology of the specimen revealed primary synovial sarcoma of left kidney.
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肾滑膜肉瘤-一种罕见的原发性恶性肿瘤
滑膜肉瘤(SS)是一种软组织肿瘤,具有独特的染色体易位t(X;18)(p11.2;q11.2),通过聚合酶链反应在组织匀浆中检测到。一名36岁女性,主诉左侧疼痛和肿块,发现有一个大肿块占据左侧,左侧胁肋和脐区,双手可触及,未越过中线。检查提示为左侧肾细胞癌,患者因此手术。术中发现肿瘤肿块累及左肾上腺,取代整个肾脏。组织病理学检查显示为原发性左肾滑膜肉瘤。
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