크론병 환자에게 아자티오프린 치료 중 발생한 비경화성 문맥 고혈압 1예

박민규, 이재광, 김현수, 정윤진, 박창근, 정재권, 김대진
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Abstract

Thiopurine-based drugs such as azathioprine and 6-MP are among the most common immunosuppressants used to treat inflammatory bowel disease, autoimmune hepatitis, various autoimmune diseases, and patients undergoing organ transplantation. The drugs are associated with various complications, of which one of the most serious is hepatotoxicity that may trigger non-cirrhotic portal hypertension. We report a case with this side-effect in a patient taking azathioprine to treat Crohn’s disease. (Korean J Med 2020;95:119-123)
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克罗恩氏症患者在阿扎替林治疗过程中发生的非经济性文脉高血压1例
硫嘌呤类药物如硫唑嘌呤和6-巯基嘌呤是最常用的免疫抑制剂,用于治疗炎症性肠病、自身免疫性肝炎、各种自身免疫性疾病和器官移植患者。这些药物与各种并发症有关,其中最严重的是肝毒性,可能引发非肝硬化门静脉高压症。我们报告一例这种副作用在病人服用硫唑嘌呤治疗克罗恩病。(韩医2020;95:119-123)
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제2형 당뇨병 환자에서 장기간의 Sodium-glucose Cotransporter 2 억제제 치료가 신장기능에 미치는 효과 16세 청소년에서 발생한 2형 자가면역 췌장염 크론병 환자에게 아자티오프린 치료 중 발생한 비경화성 문맥 고혈압 1예 국가 폐암 검진 [Pleural biopsy].
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