To evaluate the extravascular lung water in patients of bilateral lung transplantation with lung ultrasonography and SDC-1

Abstract

Objective The purpose of this study was to explore new method for evaluating the severity of extravascular lung water in patients after bilateral lung transplantation. Methods The study was performed in 50 patients after bilateral lung transplantation in our hospital from 2017 to 2018. Picco were implanted during the operation .Two hours after the operation, a doctor monitored the index of EVLWI and PVPI.At the same time, another doctor carried out examination of lung ultrasonography and Calculated the numbers of B line. After ultrasonography, the doctor used ELISA to determine the level of SDC-1. Results EVLWI were significantly correlated with the number of B-line and the level of SDC-1 (RS=0.833, RS=0.747, P<0.05), PVPI were significantly correlated with the number of B-line and the level of SDC-1 (RS=0.738, RS=0.626, P<0.05). Conclusion The number of B-line and the level of SDC-1 have a good correlation with extravascular lung water. The combination of the two indicators might be used as a reliable index for evaluating the degree of extravascular lung water after bilateral lung transplantation. Key words: Bilateral lung transplantation; EVLWI; Lung ultrasonography; SCD-1