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Single stage trans-apical TAVR and trans-femoral TEVAR for severe AR concomitant with Stanford type B aortic dissection 重度AR合并Stanford B型主动脉夹层的单期经根尖TAVR和经股TEVAR
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-0814-00270
Y. Xue, Qing Zhou, Shuchun Li, Dongjin Wang
1例严重主动脉瓣关闭不全合并Stanford B型主动脉夹层的69岁男患者,接受一期经心尖经导管主动脉瓣置换术和经股动脉胸主动脉腔内修复术。使用单分支覆膜支架,近端锚定区为Zone 2,微创Castor支架覆盖左锁骨下动脉同时单分支重建。左前胸外侧切口,经心尖经导管主动脉瓣置换术治疗主动脉瓣关闭不全,术前CT评估选择27 mm J-Valve瓣膜,释放过程中未发生瓣膜移位等问题。患者术后恢复良好,病情平稳。CT及超声心动图复查均显示良好的结果。
1例严重主动脉瓣关闭不全合并Stanford B型主动脉夹层的69岁男患者,接受一期经心尖经导管主动脉瓣置换术和经股动脉胸主动脉腔内修复术。使用单分支覆膜支架,近端锚定区为Zone 2,微创Castor支架覆盖左锁骨下动脉同时单分支重建。左前胸外侧切口,经心尖经导管主动脉瓣置换术治疗主动脉瓣关闭不全,术前CT评估选择27 mm J-Valve瓣膜,释放过程中未发生瓣膜移位等问题。患者术后恢复良好,病情平稳。CT及超声心动图复查均显示良好的结果。
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引用次数: 0
Surgical management of acute type A aortic dissection with cerebral malperfusion 急性A型主动脉夹层伴脑灌注不良的外科治疗
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20190806-00263
Jian Li, W. Qin, C. Su, F. Huang
Objective To summarize the surgical treatment and it’s results of patients with acute type A aortic dissection with cerebral malperfusion. Methods We collected and analyzed the clinical date of 16 patients, who were hospitalized and underwent operation Between January 2010 to June 2019, presented cerebral malperfusion due to acute type A aortic dissection. All of them showed preoperative newly developed neurologic deficits, left hemiplegia in 8 cases, left paraparesis in 5 cases and right paraparesis in 3 cases. Results Aortic valve was involved in 5 patients, 2 of whom underwent AVR surgery, 2 cases of CABG and 2 cases of artificial graft bypass were performed at the same time, 1 case underwent left leg amputation postoperatively. Seven patients died after surgery. Conclusion The results of surgical management of acute type A aortic dissection with cerebral malperfusion demonstrated high hospital mortality, which needs us to restore the cerebral perfusion as soon as possible. The specific method should be decided according to the patients' condition. Key words: Acute type A aortic dissection; Cerebral malperfusion
目的总结急性A型主动脉夹层合并脑灌注不良的手术治疗及效果。方法收集2010年1月至2019年6月收治的16例急性A型主动脉夹层脑灌注不良患者的临床资料并进行分析。术前均出现新发神经功能缺损,左侧偏瘫8例,左侧截瘫5例,右侧截瘫3例。结果5例患者累及主动脉瓣,其中2例行AVR手术,2例同时行冠脉搭桥和人工搭桥,1例术后行左腿截肢。7名患者在手术后死亡。结论急性A型主动脉夹层合并脑灌注不良的手术治疗结果显示住院死亡率高,需要尽快恢复脑灌注。具体方法应根据患者的情况而定。关键词:急性A型主动脉夹层;脑malperfusion
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引用次数: 0
Lung protection of remote limb ischemic preconditioning after pulmonary resection 肺切除术后远端肢体缺血预处理的肺保护作用
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20190618-00206
Maimaiti Tuerxunayi, Aimaiti Abulikemu, M. Ning, Jia-rong Xu, Jiazheng Xu, Hai-ping Ma
Objective To evaluate lung protection of remote limb ischemic preconditioning after pulmonary resection. Methods Methods sixty adult patients scheduled for elective pulmonary resection, were randomly divided into control group(group C, 30 cases) and remote limb ischemic preconditioning(group RLIP, 30 cases) using a random number table. Before one-lung-ventilation(T0), at 30 minites, 1 hour and 2 hours of OLV(T1, 2, 3), 15minites after re-expansion of the collapsed lung(T4), blood samples were drawn from the radial artery and vein for blood gas analysis, alveolar-arterial oxygen gradient(A-aDO2)、pulmonary shunt ratio(Qs/Qt)were calculated. Extraction time of closed thoracic drainage tube, length of hospital stay, the incidence of in-hospital complications after operation were recorded. Results Compared to T0 , each group at T1-T4, A-aDO2 were obviously increased. We found that at T3, A-aDO2 of group C increased much more higher and statistically significant(P 0.05). Conclusion Remote limb ischemic preconditioning had some protective effect after pulmonary resection, which mechanism may be related to enhancing autophagy in the operated 1ung tissues of the patients. Key words: Ischemic preconditioning; One-lung ventilation; Autophagy; Lung protection; Pulmonary shunt
目的探讨肺切除术后远端肢体缺血预处理对肺的保护作用。方法采用随机数字表法将60例成人择期肺切除术患者随机分为对照组(C组,30例)和远端肢体缺血预处理组(RLIP组,30例)。单肺通气前(T0)、OLV 30min、1h、2h (T1、2、3)、萎陷肺再扩张后15min (T4)分别取桡动脉、静脉采血进行血气分析,计算肺泡-动脉氧梯度(A-aDO2)、肺分流比(Qs/Qt)。记录两组患者闭式胸腔引流管拔管时间、住院时间、术后院内并发症发生率。结果与T0比较,T1-T4各组A-aDO2均明显升高。T3时,C组A-aDO2升高幅度更大,差异有统计学意义(P < 0.05)。结论远端肢体缺血预处理在肺切除术后具有一定的保护作用,其机制可能与增强患者手术后肺组织的自噬有关。关键词:缺血预处理;侧通风;自噬;肺保护;肺分流
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引用次数: 0
Cardiac function support after ALCAPA operation and its early outcome ALCAPA术后心功能支持及早期预后
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CM112434-20190212-00034
Zhihao Li, Jiming Cai, Zhuoming Xu, Haibo Zhang, Jinghao Zheng
Objective To summarize cardiac function feature and its support method after ALCAPA(anomalous origin of left coronary arteries from pulmonary artery) operation. Analysis its early outcome and risk factors of its mortality. Methods Review the clinical data of 108 ALCAPA cases treated in Shanghai Children Center between January 2005 and December 2017. All the cases were divided into two groups according to their ages when they received the surgery: group 1 1yr. Adopted LVEF(left ventricle ejection fraction) and LVEDD(left ventricle end-diastolic diameter) Z-score as a parameter to describe the cardiac function change after operation. Summarize the selection and application of vasoactive agents and its score(VIS) after operation, indirectly reflect the post-operative cardiac function. Analysis the opportunityofinitiation and termination of mechanical circulation support and the timefor mechanical ventilationevacuation. Adopt the logistic analysis to find the risk factors of early death risk factors after ALCAPA operation. Results Cardiac function had little improve in early period after ALCAPAoperation, did not attained normal range in fifth day post-operative, LVEF was 0.42 in group 1 and 0.45 in group 2, respectively. The application of vasoactive agents tended to choose α, β receptor-agonist, which epinephrine and norepinephrine is the preferred and VIS score was high in early period. Mechanical circulation support was used in 18 cases. 12 cases died in our group, mortality was 11%. Logistic regression analysis implied that low age and low level of LVEF before operation is the risk factor for mortality. Conclusion Cardiac function was still in low level in early period after ALCAPA operation, depended on higher dosage of vasoactive agents and mechanical circulation support if necessary. We recommend the LVEF index for evacuated from mechanical circulation support and mechanical ventilation is over 0.40 and 0.35 respectively, and other clinical sign should be considered simultaneously. Low age and low LVEF level before operation is the risk factors for early death after ALCAPA operation. Key words: Congenital heart disease; ALCAPA; Vasoactive agents; Mechanical circulation support
目的总结左冠状动脉异常起源肺动脉手术后的心功能特点及支持方法。分析其早期结局及死亡危险因素。方法回顾2005年1月至2017年12月上海儿童中心收治的108例ALCAPA患儿的临床资料。所有病例根据患者接受手术时的年龄分为两组:11岁组。采用左心室射血分数(LVEF)和左心室舒张末期内径(LVEDD) Z-score作为描述术后心功能变化的参数。总结血管活性药物的选择和应用及其术后评分(VIS),间接反映术后心功能。分析机械循环支持的启动和终止时机及机械通风疏散时间。采用logistic分析方法寻找ALCAPA术后早期死亡的危险因素。结果alcapa术后早期心功能无明显改善,术后第5天未达到正常范围,LVEF 1组为0.42,2组为0.45。血管活性药物的应用倾向于选择α, β受体激动剂,其中肾上腺素和去甲肾上腺素是首选,早期VIS评分较高。18例采用机械循环支架。本组死亡12例,死亡率11%。Logistic回归分析提示术前低年龄和低水平LVEF是导致死亡的危险因素。结论ALCAPA术后早期心功能仍处于较低水平,需加大血管活性药物的剂量,必要时需给予机械循环支持。我们建议脱离机械循环支持和机械通气的LVEF指数分别大于0.40和0.35,同时考虑其他临床症状。术前低年龄和低LVEF水平是ALCAPA术后早期死亡的危险因素。关键词:先天性心脏病;ALCAPA;作用于血管的药物;机械循环支架
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引用次数: 0
Population-based research of pulmonary subsolid nodule CT screening and artificial intelligence application 基于人群的肺实性结节CT筛查及人工智能应用研究
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20191126-00420
Feng Yang, Jun Fan, Junyi Tianzhou, Fan Yang, Yun Li, Xianping Liu, Jian-feng Li, G. Jiang, Jun Wang
Objective To investigate the application of low-dose chest CT(LDCT) in the screening of pulmonary subsolid nodules in population and the application value of artificial intelligence. Methods People who received chest LDCT screening between January 2015 and December 2017 were included. A retrospective study was developed to analyze the enrolled population features , detection of pulmonary subsolid nodules and independent predictors of subsolid nodules , and to evaluate the accuracy of the artificial intelligence reading method. Results Result of three cross-sectional studies reveals that the detection rates of pulmonary subsolid nodules were 0.42%, 0.69% and 0.92% in three rounds. 726 cases who completed the three rounds of screening were included in the cohort study. The cohort population was predominantly male(83.2%), with a median age of 43 years, and nearly half of the subjects(47.0%) had a history of smoking. GEE revealed that the patient's family history of lung cancer(OR=8.753, 95%CI: 1.877-40.816, P=0.006) was an independent predictor of the detection of subsolid nodules. In the 110 kVp tube voltage group, AUC of AI model was 0.740, and AUC of the manual reading method was 0.721, no significant differences were observed(P=0.502); when the preseted cutoff value of AI model was 0.75, the NRI was -0.15, indicating the accuracy of AI model was inferior to manual method(P=0.006). In the 130 kVp tube voltage group, AUC of the model was 0.888, and AUC of the manual reading method was 0.756, no significant differences were observed(P=0.128); and the NRI was 0.19, indicating the accuracy of AI model was not inferior to manual method(P=0.123). Conclusion This population' s detection rates of pulmonary subsolid nodules were 0.42%-0.92%. Family history of lung cancer was an independent predictor of subsolid pulmonary nodules. The result of AI pulmonary nodule detection model could be a reference when the training set data parameters match the actual application parameters. Key words: Lung neoplasms; Cancer screening; Multidetector computed tomography; Subsolid nodule; Artificial intelligence
目的探讨低剂量胸部CT(LDCT)在人群肺亚实性结节筛查中的应用及人工智能的应用价值。方法纳入2015年1月至2017年12月期间接受胸部LDCT筛查的患者。我们开展了一项回顾性研究,分析入组人群特征、肺亚实性结节的检测和亚实性结节的独立预测因素,并评估人工智能阅读方法的准确性。结果三次横断面研究结果显示,三轮肺实下结节检出率分别为0.42%、0.69%和0.92%。726例完成三轮筛查的患者被纳入队列研究。队列人群以男性为主(83.2%),中位年龄为43岁,近一半的受试者(47.0%)有吸烟史。结果显示,患者的肺癌家族史(OR=8.753, 95%CI: 1.877-40.816, P=0.006)是检测亚实性结节的独立预测因子。在110 kVp管电压组,AI模型的AUC为0.740,手工阅读法的AUC为0.721,差异无统计学意义(P=0.502);当人工智能模型的预设截断值为0.75时,NRI为-0.15,表明人工智能模型的准确率低于人工方法(P=0.006)。130 kVp管电压组,模型的AUC为0.888,手工读数法的AUC为0.756,差异无统计学意义(P=0.128);NRI为0.19,表明人工智能模型的准确率不低于人工方法(P=0.123)。结论该人群肺实下结节检出率为0.42% ~ 0.92%。肺癌家族史是肺实性结节的独立预测因子。当训练集数据参数与实际应用参数匹配时,人工智能肺结节检测模型的结果可作为参考。关键词:肺肿瘤;癌症筛查;多检测器计算机断层扫描;Subsolid结节;人工智能
{"title":"Population-based research of pulmonary subsolid nodule CT screening and artificial intelligence application","authors":"Feng Yang, Jun Fan, Junyi Tianzhou, Fan Yang, Yun Li, Xianping Liu, Jian-feng Li, G. Jiang, Jun Wang","doi":"10.3760/CMA.J.CN112434-20191126-00420","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112434-20191126-00420","url":null,"abstract":"Objective \u0000To investigate the application of low-dose chest CT(LDCT) in the screening of pulmonary subsolid nodules in population and the application value of artificial intelligence. \u0000 \u0000 \u0000Methods \u0000People who received chest LDCT screening between January 2015 and December 2017 were included. A retrospective study was developed to analyze the enrolled population features , detection of pulmonary subsolid nodules and independent predictors of subsolid nodules , and to evaluate the accuracy of the artificial intelligence reading method. \u0000 \u0000 \u0000Results \u0000Result of three cross-sectional studies reveals that the detection rates of pulmonary subsolid nodules were 0.42%, 0.69% and 0.92% in three rounds. 726 cases who completed the three rounds of screening were included in the cohort study. The cohort population was predominantly male(83.2%), with a median age of 43 years, and nearly half of the subjects(47.0%) had a history of smoking. GEE revealed that the patient's family history of lung cancer(OR=8.753, 95%CI: 1.877-40.816, P=0.006) was an independent predictor of the detection of subsolid nodules. In the 110 kVp tube voltage group, AUC of AI model was 0.740, and AUC of the manual reading method was 0.721, no significant differences were observed(P=0.502); when the preseted cutoff value of AI model was 0.75, the NRI was -0.15, indicating the accuracy of AI model was inferior to manual method(P=0.006). In the 130 kVp tube voltage group, AUC of the model was 0.888, and AUC of the manual reading method was 0.756, no significant differences were observed(P=0.128); and the NRI was 0.19, indicating the accuracy of AI model was not inferior to manual method(P=0.123). \u0000 \u0000 \u0000Conclusion \u0000This population' s detection rates of pulmonary subsolid nodules were 0.42%-0.92%. Family history of lung cancer was an independent predictor of subsolid pulmonary nodules. The result of AI pulmonary nodule detection model could be a reference when the training set data parameters match the actual application parameters. \u0000 \u0000 \u0000Key words: \u0000Lung neoplasms; Cancer screening; Multidetector computed tomography; Subsolid nodule; Artificial intelligence","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"52 1","pages":"145-150"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84705902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Strategies for emergency cardiovascular surgery under the epidemic of COVID-19 新冠肺炎疫情下心血管外科急诊救治策略
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20200222-00065
Xingjian Hu, N. Dong, Jiawei Shi, J. Xia
Severe acute respiratory infection caused by a novel coronavirus(SARS-CoV-2), WHO named COVID-19, is the major clinical concern globally. Both the world health organization and the National Health Commission have issued interim guidelines and management strategy for the diagnosis and treatment of COVID-19. These comprehensive guidelines establish the basic norms for the clinical practice. However, cardiovascular diseases have their special pathophysiological characteristics. The surgical treatment strategies for emergency and critical cardiovascular diseases requires specific recommendations or guidelines. From 16 January to 12 February 2020, the department of cardiovascular surgery in Wuhan Union Hospital had performed 15 emergency cardiovascular operations. The perioperative success rate is 100%. Based on our clinical practice, we summarized the relevant experience as a complement to the WHO and National Health Commission guidelines, hope to provide references for the cardiovascular surgeons. Key words: COVID-19; Cardiovascular surgery; Emergency operation; Therapeutic strategy
由世卫组织命名为COVID-19的新型冠状病毒(SARS-CoV-2)引起的严重急性呼吸道感染是全球主要的临床问题。世界卫生组织和国家卫生健康委员会发布了新冠肺炎诊疗暂行指南和管理战略。这些综合指南为临床实践建立了基本规范。然而,心血管疾病有其特殊的病理生理特点。急诊和危重心血管疾病的外科治疗策略需要具体的建议或指南。2020年1月16日至2月12日,武汉协和医院心血管外科共实施急诊心血管手术15例。围手术期成功率100%。结合临床实践,总结相关经验,作为对世界卫生组织和国家卫生健康委员会指南的补充,希望能为心血管外科医生提供参考。关键词:COVID-19;心血管外科;紧急操作;治疗策略
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引用次数: 0
Proximal and mid-term results of mitral valve repair for Barlow’s disease induced mitral insufficiency Barlow病致二尖瓣功能不全二尖瓣修复术的近中期结果
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20190528-00177
Jie Han, Baiyu Tian, Yuqing Jiao, Xu Meng
2013年1月至2018年8月在我瓣膜中心确诊二尖瓣黏液样变(Barlow综合征)并由单一术者进行二尖瓣修复手术的患者,经筛选入组25例。回顾术前超声心动图资料,术中二尖瓣修复技术,观察患者近、中期的治疗效果。25例患者中,24例修复效果满意,1例因修复失败术中改为二尖瓣置换术,成形成功率98.9%。所有患者均术后恢复良好,无并发症及死亡发生,均正常出院。术中体外循环(93.47±22.69)min,阻断(68.57±14.67)min。二尖瓣均采用人工瓣膜成形环,尺寸36(34,40)mm。术后住院(7.2±3.3)天。出院前复查超声心动图,二尖瓣微量反流15例,二尖瓣轻度反流9例。随访3~71个月,平均36.5个月。随访期间无患者死亡,无心血管不良事件,无再次心脏手术发生。二尖瓣修复术治疗Barlow综合征导致二尖瓣关闭不全的近、中期临床效果满意。
2013年1月至2018年8月在我瓣膜中心确诊二尖瓣黏液样变(Barlow综合征)并由单一术者进行二尖瓣修复手术的患者,经筛选入组25例。回顾术前超声心动图资料,术中二尖瓣修复技术,观察患者近、中期的治疗效果。25例患者中,24例修复效果满意,1例因修复失败术中改为二尖瓣置换术,成形成功率98.9%。所有患者均术后恢复良好,无并发症及死亡发生,均正常出院。术中体外循环(93.47±22.69)min,阻断(68.57±14.67)min。二尖瓣均采用人工瓣膜成形环,尺寸36(34,40)mm。术后住院(7.2±3.3)天。出院前复查超声心动图,二尖瓣微量反流15例,二尖瓣轻度反流9例。随访3~71个月,平均36.5个月。随访期间无患者死亡,无心血管不良事件,无再次心脏手术发生。二尖瓣修复术治疗Barlow综合征导致二尖瓣关闭不全的近、中期临床效果满意。
{"title":"Proximal and mid-term results of mitral valve repair for Barlow’s disease induced mitral insufficiency","authors":"Jie Han, Baiyu Tian, Yuqing Jiao, Xu Meng","doi":"10.3760/CMA.J.CN112434-20190528-00177","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112434-20190528-00177","url":null,"abstract":"2013年1月至2018年8月在我瓣膜中心确诊二尖瓣黏液样变(Barlow综合征)并由单一术者进行二尖瓣修复手术的患者,经筛选入组25例。回顾术前超声心动图资料,术中二尖瓣修复技术,观察患者近、中期的治疗效果。25例患者中,24例修复效果满意,1例因修复失败术中改为二尖瓣置换术,成形成功率98.9%。所有患者均术后恢复良好,无并发症及死亡发生,均正常出院。术中体外循环(93.47±22.69)min,阻断(68.57±14.67)min。二尖瓣均采用人工瓣膜成形环,尺寸36(34,40)mm。术后住院(7.2±3.3)天。出院前复查超声心动图,二尖瓣微量反流15例,二尖瓣轻度反流9例。随访3~71个月,平均36.5个月。随访期间无患者死亡,无心血管不良事件,无再次心脏手术发生。二尖瓣修复术治疗Barlow综合征导致二尖瓣关闭不全的近、中期临床效果满意。","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"27 1","pages":"185-187"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89368782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The clinical outcomes of myocardial incision and tearing for the treatment of myocardial bridge 心肌切开撕裂治疗心肌桥的临床效果
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20190601-00183
Yong Mao, Wensheng Chen, Yalin Wei, Xinqiang Guan, Yanchun Zhang, Xiangyang Wu
Objective To analyze clinical outcomes of myocardial incision and tearing for the treatment of myocardial bridge. Methods A retrospective cohort study was conduct to review the clinical date of 29 patients who underwent surgical myotomy from January 2014 to January 2018 in the Second Hospital of Lanzhou University. A total of 11 patients(incision group) were experienced traditional myotomy on myocardial bridge that the myocardium was longitudinally incised along the direction of the coronary artery, while 18 patients(tearing group) were treated by myocardial incision combined with tearing that longitudinally incised myocardium and deeply tissue tearing. The operation time of surgical myotomy, the amount of bleeding, the number of branches of vascular injury and the number of ventricular ruptures during operation were compared between the two groups. After followed up half a year to one year, the clinical symptoms of angina pectoris, myocardial ischemia by electrocardiogram suggested, and coronary stenosis by coronary CT suggested were collected. Results The operation time of surgical myotomy, the amount of bleeding patients and the number of branches of vascular injury during operation in the incision group were higher than those in the tearing group(P 0.05). After followed up half a year to one year, there was no significant difference in the clinical symptoms of angina pectoris, myocardial ischemia by electrocardiogram suggested, and coronary stenosis by coronary CT suggested(P>0.05). Conclusion Myocardial incision combined with tearing is a surgical procedure with short operation time and low bleeding risk, which is more beneficial than the traditional longitudinally incised for the myocardial bridge. Key words: Myocardial bridge; Myotomy; Clinical outcome
目的分析心肌切开撕裂治疗心肌桥的临床效果。方法回顾性分析兰州大学第二医院2014年1月至2018年1月29例行肌切开术患者的临床资料。共有11例患者(切口组)采用沿冠状动脉方向纵向切开心肌的传统心肌桥切开术,18例患者(撕裂组)采用纵向切开心肌并深层撕裂的心肌切口联合撕裂术。比较两组手术切开术时间、术中出血量、血管损伤分支数及脑室破裂次数。随访半年至一年,收集心电图提示的心绞痛、心肌缺血、冠状动脉CT提示的冠状动脉狭窄的临床症状。结果切开组手术切肌时间、术中出血患者数量及血管损伤分支数均高于撕裂组(P < 0.05)。随访半年至1年,两组心绞痛临床症状、心电图提示心肌缺血、冠状动脉CT提示冠状动脉狭窄差异无统计学意义(P>0.05)。结论心肌切开联合撕裂是一种手术时间短、出血风险低的手术方式,比传统的纵向切开心肌桥更有利。关键词:心肌桥;肌切开术;临床结果
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引用次数: 0
Effect of transcatheter occlusion of azygos/hemiazygos vein in patients with venous stealing after the bidirectional Glenn procedure-analysis of 24 cases 经导管阻断奇偶静脉/半奇偶静脉在双向Glenn手术后静脉窃取患者中的作用——附24例分析
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20190831-00291
C. Dai, B. Guo, Y. Ling, Lingxiao Chen, M. Jin
Objective To observe and follow up the effect of transcatheter occlusion of the azygos/hemiazygos veins in patients with complex congenital heart diseases and venous stealing after bidirectional Glenn procedure, who had not meet the criteria of total cavopulmonary connection(TCPC) or corrective operation. Methods This article analyzed retrospectively and followed up the effect of transcatheter occlusion of the azygos/hemiazygos vein in patients after bidirectional Glenn procedure hospitalized during February 2012 to September 2017. Results Transcatheter occlusions of azygos veins were performed in 21 patients and left superior vena cava(LSVC) was occluded in one of patients meanwhile. Azygos veins and hemiazygos veins were both occluded in two patients. One patient had the hemiazygos vein occluded. Aortic-to-pulmonary collaterals were occluded in 6 patients in the meantime. Atrial septal defect occluders were applied in the transcatheter occlusions of azygos veins, hemiazygos veins and LSVC, except one patient with an azygos vein which was 5.5 mm in diameter. Saturation was increased from 0.78 to 0.85 through occlusion(P 0.05). No complications associated with interventional procedures occurred. There was no significant decrease in blood oxygen saturation. Facial and upper limb edema, varicose veins in the chest and abdominal wall, pleural effusion and peritoneal effusion did not happen during follow up of 2 years. Two patients underwent TCPC operation one year and five years after interventional occlusion separately. Conclusion Transcatheter occlusion of azygos/hemiazygos vein or PLSVC was feasible in patients with complex congenital heart diseases and venous stealing after bidirectional Glenn procedure on the premise of choosing suitable indications. Suitable indications meant that the pressure of pulmonary artery and superior vena cava was less than 20 mmHg in the basal state, and the pressure of superior vena cava was also less than 20 mmHg before the release of the occluder. Occlusions may increase the oxygen saturation of patients, improve the quality of life, and even promote the development of pulmonary vascular bed, so as to achieve the indications of TCPC operation in some patients. Key words: Azygos vein; Hemiazygos vein; Transcatheter closure; Bidirectional Glenn procedure
目的观察并随访复杂先天性心脏病患者双向Glenn手术后静脉窃取,未达到全腔肺连接(TCPC)标准或未行矫形手术的经导管阻断奇/半奇静脉的效果。方法回顾性分析2012年2月至2017年9月住院的双向Glenn手术后经导管阻断奇静脉/半奇静脉的效果并进行随访。结果21例奇静脉经导管闭塞,1例左上腔静脉闭塞。两例患者均有奇静脉和半奇静脉闭塞。1例患者半斜静脉闭塞。同时有6例主肺侧支闭塞。除1例奇静脉直径5.5 mm外,房间隔缺损封堵器均应用于奇静脉、半奇静脉、左室静脉经导管封堵。闭塞后饱和度由0.78提高到0.85 (p0.05)。无介入手术相关并发症发生。血氧饱和度无明显下降。随访2年未发生面部及上肢水肿、胸腹壁静脉曲张、胸腔积液及腹膜积液。2例患者在介入闭塞后1年和5年分别行TCPC手术。结论在选择合适的适应症的前提下,对双向Glenn手术后静脉窃取的复杂先天性心脏病患者,经导管阻断奇/半奇静脉或PLSVC是可行的。合适的适应症是指在基础状态下肺动脉和上腔静脉压力小于20mmhg,在释放封堵器前上腔静脉压力也小于20mmhg。闭塞可使患者血氧饱和度升高,改善生活质量,甚至促进肺血管床的发育,从而达到部分患者TCPC手术的指征。关键词:奇静脉;Hemiazygos静脉;经导管关闭;双向格伦法
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引用次数: 0
Impact of interstitial lung disease on postoperative morbidity and 60 day mortality after pulmonary resection for lung cancer 间质性肺疾病对肺癌肺切除术后术后发病率和60天死亡率的影响
Pub Date : 2020-03-25 DOI: 10.3760/CMA.J.CN112434-20190818-00273
Weipeng Shao, Jingjing Huang, J. Zhang, Shanwu Ma, Hongxiang Feng, Hongliang Sun, Yanhong Ren, Xiaowei Wang, Zhen-rong Zhang, Deruo Liu
Objective To evaluate the effect of interstitial lung disease(ILD) on postoperative morbidity and mortality in pulmonary resection for lung cancer patients. Methods We retrospectively analyzed 971 patients undergoing pulmonary operation from January 2010 to January 2018 in our hospital. Clinical data including age, sex, history of chronic obstructive pulmonary disease(COPD), smoking history, smoking index, American Society of Anesthesiologists(ASA) classification, forced expiratory volume in 1 s(FEV1) % predict, surgical procedure, video assisted thoracoscopic surgery(VATS) or not, intraoperative blood transfusion, anesthesia time, operation time/one-lung ventilation time, blood loss, histology, postoperative morbidity, 60-days mortality, onset of acute exacerbation of interstitial lung disease(AE-ILD), drainage, extubation time, and postoperative stay were collected and analyzed. Results There were 80(8.2%) and 891(91.8%) patients in ILD and non-ILD group, respectively. AE-ILD occurred in 5 patients, with a 60-day mortality of 80%. A multivariate regression analysis identified that the sex(P=0.023), ILD(P=0.001), COPD(P=0.027) were independent risk factors for postoperative morbidity. ILD(P=0.023) and postoperative morbidity(P=0.001) were independent risk factors for 60-day mortality in multivariate analysis. Conclusion Patients with ILD had a higher incidence of postoperative morbidity and 60-day mortality. Based on the obvious postoperative morbidity and mortality, special attention and management should be taken in ILD patients. Key words: ILD; Pulmonary resection; AE-ILD; Morbidity; 60-day mortality
目的探讨间质性肺疾病(ILD)对肺癌肺切除术患者术后发病率和死亡率的影响。方法回顾性分析2010年1月至2018年1月在我院行肺部手术的971例患者。临床资料包括年龄、性别、慢性阻塞性肺疾病(COPD)史、吸烟史、吸烟指数、美国麻醉医师学会(ASA)分级、用力呼气量在1秒内(FEV1) %预测、手术方式、视频辅助胸腔镜手术(VATS)与否、术中输血、麻醉时间、手术时间/单肺通气时间、出血量、组织学、术后发病率、60天死亡率、收集并分析间质性肺疾病急性加重(AE-ILD)的发病、引流、拔管时间和术后住院时间。结果ILD组80例(8.2%),非ILD组891例(91.8%)。5例患者发生AE-ILD, 60天死亡率为80%。多因素回归分析发现,性别(P=0.023)、ILD(P=0.001)、COPD(P=0.027)是术后发病率的独立危险因素。多因素分析显示,ILD(P=0.023)和术后发病率(P=0.001)是60天死亡率的独立危险因素。结论ILD患者术后发病率和60天死亡率较高。基于术后明显的发病率和死亡率,ILD患者应特别重视和处理。关键词:ILD;肺切除术;AE-ILD;发病率;60天的死亡率
{"title":"Impact of interstitial lung disease on postoperative morbidity and 60 day mortality after pulmonary resection for lung cancer","authors":"Weipeng Shao, Jingjing Huang, J. Zhang, Shanwu Ma, Hongxiang Feng, Hongliang Sun, Yanhong Ren, Xiaowei Wang, Zhen-rong Zhang, Deruo Liu","doi":"10.3760/CMA.J.CN112434-20190818-00273","DOIUrl":"https://doi.org/10.3760/CMA.J.CN112434-20190818-00273","url":null,"abstract":"Objective \u0000To evaluate the effect of interstitial lung disease(ILD) on postoperative morbidity and mortality in pulmonary resection for lung cancer patients. \u0000 \u0000 \u0000Methods \u0000We retrospectively analyzed 971 patients undergoing pulmonary operation from January 2010 to January 2018 in our hospital. Clinical data including age, sex, history of chronic obstructive pulmonary disease(COPD), smoking history, smoking index, American Society of Anesthesiologists(ASA) classification, forced expiratory volume in 1 s(FEV1) % predict, surgical procedure, video assisted thoracoscopic surgery(VATS) or not, intraoperative blood transfusion, anesthesia time, operation time/one-lung ventilation time, blood loss, histology, postoperative morbidity, 60-days mortality, onset of acute exacerbation of interstitial lung disease(AE-ILD), drainage, extubation time, and postoperative stay were collected and analyzed. \u0000 \u0000 \u0000Results \u0000There were 80(8.2%) and 891(91.8%) patients in ILD and non-ILD group, respectively. AE-ILD occurred in 5 patients, with a 60-day mortality of 80%. A multivariate regression analysis identified that the sex(P=0.023), ILD(P=0.001), COPD(P=0.027) were independent risk factors for postoperative morbidity. ILD(P=0.023) and postoperative morbidity(P=0.001) were independent risk factors for 60-day mortality in multivariate analysis. \u0000 \u0000 \u0000Conclusion \u0000Patients with ILD had a higher incidence of postoperative morbidity and 60-day mortality. Based on the obvious postoperative morbidity and mortality, special attention and management should be taken in ILD patients. \u0000 \u0000 \u0000Key words: \u0000ILD; Pulmonary resection; AE-ILD; Morbidity; 60-day mortality","PeriodicalId":10181,"journal":{"name":"Chinese Journal of Thoracic and Cardiovaescular Surgery","volume":"48 1","pages":"140-144"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88240351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Chinese Journal of Thoracic and Cardiovaescular Surgery
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