Comparative study on the bioavailability of peptide extracts from Jeju black pigs and three-way crossbred pigs.

IF 2.7 3区农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Journal of Animal Science and Technology Pub Date : 2024-09-01 Epub Date: 2024-09-30 DOI:10.5187/jast.2023.e86

Jae Won Jeong, Ermie Mariano, Da Young Lee, Seung Yun Lee, Jae Hyeon Kim, Seung Hyeon Yun, Juhyun Lee, Jinmo Park, Yeongwoo Choi, Dahee Han, Jin Soo Kim, Sun Jin Hur

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Abstract

This study aimed to compare the changes in the bioactivities of peptide extracts (< 10 kDa) obtained from Jeju black pigs (JBP) and three-way crossbred pigs (Landrace × Yorkshire × Duroc, LYD) before and after digestion. The results showed that the loin peptide extracts of JBP maintained high 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity after in vitro digestion. However, the iron chelating activity and antihypertensive activity of all peptide extracts were decreased. This study suggested that the peptide extracts produced through alkaline-AK digestion have sufficiently high antioxidant and antihypertensive activities; however, these activities were reduced after in vitro digestion. Meanwhile, the JBP loin and ham peptide extracts promoted high superoxide dismutase (SOD) activity than that of LYD when administered to mice. Furthermore, the ham peptide extracts of JBP showed a relatively high antihypertensive activity in mice. Therefore, it is deemed that these peptide extracts from JBP are more bioactive than that of LYD, and can be used as bioactive materials.

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济州黑猪和三元杂交猪多肽提取物生物利用率的比较研究。

本研究旨在比较济州黑猪（JBP）和三元杂交猪（Landrace × Yorkshire × Duroc，LYD）的多肽提取物（< 10 kDa）在消化前后的生物活性变化。结果表明，济州黑猪的腰肽提取物在体外消化后保持了较高的 2,2'-偶氮-双（3-乙基苯并噻唑啉-6-磺酸）（ABTS）自由基清除活性。然而，所有多肽提取物的螯合铁活性和抗高血压活性均有所下降。这项研究表明，通过碱性-AK消化产生的肽提取物具有足够高的抗氧化和降压活性，但这些活性在体外消化后会降低。同时，给小鼠服用 JBP 猪腰和火腿肽提取物后，其超氧化物歧化酶（SOD）活性高于 LYD。此外，JBP 的火腿肽提取物对小鼠显示出较高的抗高血压活性。因此，可以认为 JBP 的这些肽提取物比枸杞多糖的生物活性更高，可用作生物活性材料。

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来源期刊

Journal of Animal Science and Technology Agricultural and Biological Sciences-Food Science

CiteScore

4.50

自引率

8.70%

发文量

审稿时长

7 weeks

期刊介绍： Journal of Animal Science and Technology (J. Anim. Sci. Technol. or JAST) is a peer-reviewed, open access journal publishing original research, review articles and notes in all fields of animal science. Topics covered by the journal include: genetics and breeding, physiology, nutrition of monogastric animals, nutrition of ruminants, animal products (milk, meat, eggs and their by-products) and their processing, grasslands and roughages, livestock environment, animal biotechnology, animal behavior and welfare. Articles generally report research involving beef cattle, dairy cattle, pigs, companion animals, goats, horses, and sheep. However, studies involving other farm animals, aquatic and wildlife species, and laboratory animal species that address fundamental questions related to livestock and companion animal biology will also be considered for publication. The Journal of Animal Science and Technology (J. Anim. Technol. or JAST) has been the official journal of The Korean Society of Animal Science and Technology (KSAST) since 2000, formerly known as The Korean Journal of Animal Sciences (launched in 1956).