Seasonal changes in HbA1c values from young to elderly diabetic patients

Y. Kato, H. Bando, H. Yamashita, S. Yada, Shunsuke Tokuhara, Hatsue Tokuhara, T. Mutsuda
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引用次数: 12

Abstract

Background: Current research has focused on the seasonal changes in HbA1c at the age of 21-90 years old. Subjects and methods: Subjects were 96 patients with type 2 diabetes mellitus (T2DM). Methods include the classification of group A, B, C by the age with 21-50, 51-70, 71-90 years old. HbA1c values in median were calculated for five consecutive seasons from December 2017 to February 2019. Results: BMI value in 3 group A, B, C was 29.7, 24.7, 25.3, respectively. Basal HbA1c was 7.0%, 7.1%, 7.1%, in 3 groups, respectively. Seasonal changes in HbA1c are as follows: group A showed highest in the summer, group B showed highest in the spring and gradually decreased to the winter, and group C showed gradual decrease and lowest in autumn. Discussion and conclusion: Seasonal changes would be probably from i) working generation with fatigue for persistent hot climate in group A, ii) rather stable daily life with balanced work and rest for the home in group B and C, iii) hot climate from spring to summer may be involved in the changes. Current investigation does not include multiple related factors. Further research will be expected for clarifying various factors.
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青年和老年糖尿病患者HbA1c值的季节变化
背景:目前的研究主要集中在21-90岁人群HbA1c的季节性变化。对象和方法:研究对象为96例2型糖尿病(T2DM)患者。方法按年龄分为A、B、C组,分别为21 ~ 50岁、51 ~ 70岁、71 ~ 90岁。从2017年12月至2019年2月连续5个季节计算HbA1c值的中位数。结果:A、B、C 3组患者BMI值分别为29.7、24.7、25.3。3组患者基础HbA1c分别为7.0%、7.1%、7.1%。HbA1c的季节变化为:A组夏季最高,B组春季最高,至冬季逐渐降低,C组逐渐降低,秋季最低。讨论与结论:季节的变化可能来自于A组持续炎热的气候导致的疲劳的工作一代,B组和C组相对稳定的日常生活,平衡的工作和休息的家庭,iii)春至夏的炎热气候可能涉及到这些变化。目前的调查没有包括多个相关因素。需要进一步的研究来澄清各种因素。
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