D. Bichet, Michel Bouvier, B. Chini, G. Gimpl, G. Guillon, Tadashi Kimura, M. Knepper, S. Lolait, M. Manning, B. Mouillac, A. O'Carroll, C. Serradeil‐Le Gal, M. Soloff, J. Verbalis, M. Wheatley, H. Zingg
{"title":"Vasopressin and oxytocin receptors in GtoPdb v.2023.1","authors":"D. Bichet, Michel Bouvier, B. Chini, G. Gimpl, G. Guillon, Tadashi Kimura, M. Knepper, S. Lolait, M. Manning, B. Mouillac, A. O'Carroll, C. Serradeil‐Le Gal, M. Soloff, J. Verbalis, M. Wheatley, H. Zingg","doi":"10.2218/gtopdb/f66/2023.1","DOIUrl":null,"url":null,"abstract":"Vasopressin (AVP) and oxytocin (OT) receptors (nomenclature as recommended by NC-IUPHAR [94]) are activated by the endogenous cyclic nonapeptides vasopressin and oxytocin. These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [69].","PeriodicalId":14617,"journal":{"name":"IUPHAR/BPS Guide to Pharmacology CITE","volume":"24 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IUPHAR/BPS Guide to Pharmacology CITE","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2218/gtopdb/f66/2023.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Vasopressin (AVP) and oxytocin (OT) receptors (nomenclature as recommended by NC-IUPHAR [94]) are activated by the endogenous cyclic nonapeptides vasopressin and oxytocin. These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [69].