Emulgel: A Review

Sahil Hasan, Saloni Bhandari, Ankita Sharma, Poonam Garg
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引用次数: 4

Abstract

Emulgel systems are currently attention to the pharmaceutical sectors because of their substantial potential to act as drug delivery vehicle by incorporating a broad range of drug molecules and higher stability compared to the other dosage form like cream, lotion, gel, etc. Emulsions are either available in an oil in water or water in oil type. These are prepared by the incorporation of the emulsion into the gel with constant stirring at a moderate speed. Incorporation of emulsion into a gel makes it a dual control release system, thereby, increasing its stability. It has better drug release if we compare to other topical drug delivery system. It is non greasy because of the presence of gel phase which enhances patient compliance. Gels has a major limitation for the delivery of hydrophobic drugs, so to overcome this limitation an emulsion based approach is being used so that even a hydrophobic therapeutic drug can enjoy the unique properties of gels. In recent years, these have also been a great interest in the use of novel polymers. These emulgels are having major advantages on vesicular drug delivery systems as well as on conventional systems in various aspects. Various permeation enhancers can enhance the effect; due to this emulgels can be used as better topical drug delivery systems over current drug delivery systems. The emulsion can be use for analgesics and antifungal drugs.
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乳胶:回顾
乳凝胶系统目前受到制药部门的关注,因为与乳霜、乳液、凝胶等其他剂型相比,乳凝胶系统具有通过结合广泛的药物分子和更高的稳定性而作为药物递送载体的巨大潜力。乳剂有两种,一种是油包水,一种是水包油。这些是通过将乳液掺入凝胶中,以中等速度不断搅拌而制备的。将乳液掺入凝胶中使其成为双重控制释放系统,从而增加了其稳定性。与其他外用给药系统相比,具有更好的药物释放效果。它是不油腻的,因为凝胶相的存在,提高了患者的依从性。凝胶对于疏水药物的递送有一个主要的限制,因此为了克服这一限制,正在使用基于乳液的方法,这样即使是疏水治疗药物也可以享受凝胶的独特特性。近年来,这些也得到了人们极大兴趣的新型聚合物的应用。这些乳剂在囊泡给药系统以及常规系统的各个方面都具有主要的优点。各种渗透增强剂可增强效果;由于这一点,凝胶可以用作比目前的药物输送系统更好的局部药物输送系统。乳剂可用于止痛剂和抗真菌药物。
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