Akito Tsuchiya, Aki Nishihara, A. Saeki, Yuki Teru, T. Aoki, T. Kono, M. Sakai, J. Hikima
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引用次数: 1
Abstract
― Pseudotuberculosis pathogen, Photobacterium damselae subsp. piscicida ( Pdp ) shows some differences in virulence between Japanese and US strains. In this study, we analyzed plasmid DNAs derived from Japanese and US strains of Pdp , and found two homologous regions in these plasmids, pOT-51443-4/p91-197-1 and pOT-51443-1/p91-197-2. All genes in the p91-197-1 from US strain were observed in the pOT-51443-4 from Japanese strain. This event might have occurred during transmission of the US plasmid to Japanese strain. Inhibitor of vertebrate lysozyme ( ivy ), a known pathogenicity factor was encoded in the homologous region of pOT-51443-1/p91-197-2. Thus, the genomic region containing ivy may have been horizontally transmitted between the two Pdp strains.
-假结核病原体，光杆菌damselae亚sp。Pdp在日本和美国菌株的毒力有一定差异。在本研究中，我们分析了来自日本和美国Pdp菌株的质粒dna，在这些质粒中发现了两个同源区域，pOT-51443-4/p91-197-1和pOT-51443-1/p91-197-2。美国菌株p91-197-1的基因在日本菌株pOT-51443-4中均有发现。这一事件可能发生在美国质粒向日本菌株传播的过程中。已知致病性因子-脊椎动物溶菌酶抑制剂(Inhibitor of vertebrate lysozyme, ivy)编码于pOT-51443-1/p91-197-2的同源区。因此，含有常春藤的基因组区域可能在两个Pdp菌株之间水平传播。
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