Investigation of non-HDL cholesterol and C-reactive protein in diabetes patients

Wen-Tung Hsu , Hsiu-Chuan Pien , Hai-I Huang , Yi-Yu Tu , Wu-Hsien Kuo , Kwang-Yang Tsai , Li-Mien Chen
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引用次数: 2

Abstract

Atherosclerosis is a chronic inflammatory vascular disease, and an association between elevated blood lipids and atherosclerosis has previously been recognized. Low-density lipoprotein cholesterol (LDLc) levels have also been recognized as indicators of cardiovascular complications, but two people who have exactly the same LDLc concentrations may have different risk factors, and the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) guidelines recommend patching non-high-density lipoprotein cholesterol (non-HDLc) as another indicator. The present study investigated diabetic dyslipidemia to determine if there is a correlation between dyslipidemia and C-reactive protein (CRP). The data shows that non-HDLc was an independent risk factor for cardiovascular events in patients with diabetes and that CRP could indicate the risk of future cardiovascular events in both high-risk and healthy individuals.

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糖尿病患者非高密度脂蛋白胆固醇及c反应蛋白的研究
动脉粥样硬化是一种慢性炎症性血管疾病,血脂升高与动脉粥样硬化之间的关系已被认识到。低密度脂蛋白胆固醇(LDLc)水平也被认为是心血管并发症的指标,但是两个ldl浓度完全相同的人可能有不同的危险因素,国家胆固醇教育计划成人治疗小组III (NCEP ATP III)指南建议将非高密度脂蛋白胆固醇(non-HDLc)作为另一个指标。本研究对糖尿病血脂异常进行了调查,以确定血脂异常与c反应蛋白(CRP)之间是否存在相关性。数据显示,非hdlc是糖尿病患者心血管事件的独立危险因素,CRP可以指示高危人群和健康人群未来心血管事件的风险。
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