Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective

D. Sandhu, Veenu Gupta, D. Chhina, M. Munjal
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Abstract

Objectives: Objectives: Fungal rhinosinusitis is one of the important healthcare problems and its incidence and prevalence are increasing over the past three decades. It affects approximately 20% of the population at some time in their lives. We aimed to identify and characterize the microorganisms causing non-invasive rhinosinusitis and to correlate the findings with the clinical profile of patients. Methods: Clinically suspected cases of rhinosinusitis were enrolled in the study and detailed clinical history was taken. Samples like nasal mucosa, nasal crusts, scrapings / excised nasal polyps, and biopsy were collected. The specimens were processed for fungal culture. Isolates were identified as per standard protocols. Results: A total of 74 patients clinically suspected of rhinosinusitis were enrolled in our study out of which 60.8% were males. The most common presenting complaint was nasal obstruction (91.8%) followed by nasal discharge (77%). Clinically characterizing, the most common type of non-invasive rhinosinusitis seen in our study was allergic rhinosinusitis (44.6%). KOH positivity was 45.6% and fungal culture positivity was 30.4%. The most common fungal isolate was Aspergillus flavus . Conclusion: and periodic evaluation of the patterns of isolates complications by early institution of appropriate treatment. J Microbiol Infect Dis 2021; 11(1):21-26.
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非侵入性鼻窦炎:临床和微生物学观点
目的:真菌性鼻窦炎是重要的卫生保健问题之一,近三十年来其发病率和流行率呈上升趋势。大约20%的人在一生中的某个时候都会受到影响。我们的目的是鉴定和表征引起非侵入性鼻窦炎的微生物,并将这些发现与患者的临床特征联系起来。方法:选取临床疑似鼻窦炎病例,收集详细的临床病史。收集鼻黏膜、鼻痂、刮伤/切除鼻息肉、活检等标本。对标本进行真菌培养。按照标准方案鉴定分离株。结果:共纳入74例临床疑似鼻窦炎患者,其中男性60.8%。最常见的主诉是鼻塞(91.8%),其次是流鼻液(77%)。临床特征,在我们的研究中最常见的非侵袭性鼻窦炎类型是过敏性鼻窦炎(44.6%)。KOH阳性占45.6%,真菌培养阳性占30.4%。最常见的真菌分离物是黄曲霉。结论:通过早期适当的治疗,定期评估分离性并发症的模式。中华微生物学杂志[J];11(1):。第21到26
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