{"title":"Mechanisms in retrograde amnesia: a case for biogenic amines","authors":"Perry Kurtz , Tibor Palfai","doi":"10.1016/0147-7552(77)90038-9","DOIUrl":null,"url":null,"abstract":"<div><p>Research interpretations of the mechanisms by which various treatments produce retrograde amnesia are of three general types: (1) general modification of central nervous system excitability, (2) changes in the rate of brain protein or RNA synthesis, (3) alterations of brain neurotransmitter levels. Here, we review these interpretations and, within the framework of Kety's model, suggest that normal levels of biogenic amines during a critical period of memory storage may be essential for retention.</p></div>","PeriodicalId":100157,"journal":{"name":"Biobehavioral Reviews","volume":"1 1","pages":"Pages 25-33"},"PeriodicalIF":0.0000,"publicationDate":"1977-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0147-7552(77)90038-9","citationCount":"9","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biobehavioral Reviews","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0147755277900389","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 9
Abstract
Research interpretations of the mechanisms by which various treatments produce retrograde amnesia are of three general types: (1) general modification of central nervous system excitability, (2) changes in the rate of brain protein or RNA synthesis, (3) alterations of brain neurotransmitter levels. Here, we review these interpretations and, within the framework of Kety's model, suggest that normal levels of biogenic amines during a critical period of memory storage may be essential for retention.
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