Association of Chronic Hepatitis C in Type 2 Diabetes Mellitus Patients in HMC Hospital Peshawar

Abstract

Background: Hepatitis C virus is a blood-borne virus, and the vast majority of infections are the result of blood exposure from unsafe injection practices, poor health care, unscreened blood transfusions, injection drug use, and sexual practices that result in blood exposure. Chronic (CHC) infection is caused by the hepatitis C virus, and affected nearly 198 million people worldwide. Objective:  To determine whether there was a link between hepatitis C virus infection and Diabetes Mellitus. Methodology: After receiving approval from the Hospital's Ethical Committee, this study was conducted over a one-year period (15-01-2018 to 16-01-2019) to investigate the relationship between HCV infection and D.M patient reports at the Diabetic Department of Diabetes and Endocrinology HMC Hospital in Peshawar. An enzyme-linked immunosorbent assay (ELISA) was used to measure anti-HCV antibody, as well as glycosylated hemoglobin (HbA1c) and fasting and random blood sugar levels. SPSS version 2.1 was used to analyses the data. Results: average of all patients ages (n=238) was 51.3811.35 years. Patients were split evenly between males and females, with 128 (52%) males and 110 (48%) females. In the group of type 2 D.M patients who tested positive for hepatitis C by ELISA, 44 (18.8%) had diabetes and 194 (82.2%) did not. Conclusion: Type 2 diabetes mellitus is more common Chronic Hepatitis C infection, increasing age, and a positive family history of Diabetes Mellitus according to the findings.