A STUDY OF HISTOPATHOLOGICAL CHANGES IN THE GILL AND LIVER TISSUES OF FRESHWATER FISH HETEROPNEUSTES FOSSILIS EXPOSED TO CYPERMETHRIN TOXICITY

R. Sulthana
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Abstract

The synthetic pyrethroid, cypermethrin toxicity was studied in fresh water fish 'Heteropneustes fossilis and the tissues like gill and liver were chosen for Histopathological effects by light microscopy, for 4 days and 7 days under sublethal concentrations. No Histopathological effects were observed in control group and 4 days group. Hence 7 days group was selected for the present study. Significant changes in Hepatic cells of liver were observed like cloudy swelling of hepatocytes, vacuolour degeneration, and dilation of sinusoids, Hepatic lesions, and Karyo Lexis. In Gill, oedema, Epithelial lining, curling of lamellae were observed. This study demonstrates the potential of electron microscopy in particular SEM, as a tool for detecting cypermethrin induced damage to liver and surface of gill lamellae.
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氯氰菊酯中毒后淡水鱼化石鳃和肝脏组织病理学变化的研究
研究了合成拟除虫菊酯、氯氰菊酯对淡水鱼化石的毒性作用,并选取鳃和肝脏等组织在亚致死浓度下作用4 d和7 d,光镜下进行了组织病理学观察。对照组和4 d组均未见组织病理学影响。因此,本研究选择7 d组。肝细胞有明显改变,肝细胞浑浊肿胀,空泡变性,窦状窦扩张,肝病变,核裂。鳃部水肿、上皮内层、片层卷曲。本研究证明了电子显微镜特别是扫描电镜作为检测氯氰菊酯对肝脏和鳃片表面损伤的工具的潜力。
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