Study on the change of amygdala on magnetic resonance imaging in alcoholic patients

Abstract

Objective: To determine the relationship between alcoholism and changes in amygdala morphology on magnetic resonance imaging (MRI). Subject and method: A cross-sectional descriptive study was conducted from January 2020 to June 2022 at Thai Nguyen National Hospital. The Stepwise AIC method was used to determine the optimal model related to the volume of the amygdale. Result: A total of 140 male patients were selected to participate in the study with a ratio of alcohol addicted to non-alcohol addicted being 1:1. The optimal model suggested a statistically significant relationship between alcohol addiction status and the aforementioned volume measurements. In addition, the intracranial volume was found to be positively correlated with amygdale volume. However, age was found to have a negative correlation with amygdale volume on the left side, but the correlation between age and amygdale volume on the right side was not statistically significant. Conclusion: Our study provides evidence of a relationship between alcohol addiction status and lower amygdale volume.