Trends in Particle Formation of Bioactive Compounds Using Supercritical Fluids and Nanoemulsions

M. Thereza, M. Gomes, D. Santos, M. Angela, A. Meireles
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引用次数: 25

Abstract

This review discusses the recent developments in the application of supercritical fluid technologies for the production of composites or encapsulates of bioactive compounds. Various supercritical particle formation technologies are briefly described, including processes in which the supercritical fluid acts as a solute, solvent, and antisolvent. The main features and mechanisms of antisolvent techniques that contribute to the understanding of the fundamentals of the Supercritical Fluid Extraction of Emulsions (SFEE) process are described. The published literature on SFEE, including the results and perspectives of its application in various industrial fields, are discussed. This article is the first comprehensive review specifically focused on the formation of particles using the SFEE technique.
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利用超临界流体和纳米乳液制备生物活性化合物颗粒的研究进展
本文综述了超临界流体技术在生产生物活性化合物复合材料或包封物方面的最新进展。简要介绍了各种超临界颗粒形成技术,包括超临界流体作为溶质、溶剂和反溶剂的过程。介绍了反溶剂技术的主要特点和机理,有助于理解超临界流体萃取乳剂(SFEE)过程的基本原理。讨论了SFEE的相关文献,包括其在各个工业领域的应用结果和前景。本文是第一个全面的综述,专门针对使用SFEE技术形成的颗粒。
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