Mingfei Xiao, Zhaoying Zhou, Xing Yang, Yingfei Wu, Shangfeng Liu
{"title":"Simulation and Experiment Analysis for Electrical Property of Cell Suspension by Micro Chip","authors":"Mingfei Xiao, Zhaoying Zhou, Xing Yang, Yingfei Wu, Shangfeng Liu","doi":"10.1109/NEMS.2006.334701","DOIUrl":null,"url":null,"abstract":"The physical quantity which is acquired from biological electrical impedance spectroscopy (EIS) can reflect the plentiful biological electrical characteristics. A microfabricated chip and related measurement system, which could be used for electrical impedance spectroscopy analysis, were introduced in this paper. A novel EIS measurement method is emerging. Based on the preliminary experimental results, the HeLa cell suspensions with different physiological status could be measured and distinguished. A 6-elements equivalent circuit model was used to simulate the experimental results. The micro chip has some advantages, such as high resolution and ease of operation. It shows application potentials in the fields of cellular electrophysiology, drug screening and bio-sensors, etc","PeriodicalId":6362,"journal":{"name":"2006 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"35 1","pages":"1216-1219"},"PeriodicalIF":0.0000,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2006 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NEMS.2006.334701","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
The physical quantity which is acquired from biological electrical impedance spectroscopy (EIS) can reflect the plentiful biological electrical characteristics. A microfabricated chip and related measurement system, which could be used for electrical impedance spectroscopy analysis, were introduced in this paper. A novel EIS measurement method is emerging. Based on the preliminary experimental results, the HeLa cell suspensions with different physiological status could be measured and distinguished. A 6-elements equivalent circuit model was used to simulate the experimental results. The micro chip has some advantages, such as high resolution and ease of operation. It shows application potentials in the fields of cellular electrophysiology, drug screening and bio-sensors, etc
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